Structure of PDB 6gzx Chain P4 Binding Site BS01

Receptor Information
>6gzx Chain P4 (length=84) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVKIRLARFGSKHNPHYRIVVTDARRKRDGKYIEKIGYYDPRKTTPDWLK
VDVERARYWLSVGAQPTDTARRLLRQAGVFRQEA
Ligand information
>6gzx Chain A4 (length=1506) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
ccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucg
ugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguu
aguugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcg
ggaggaaggaggggacgacgucuggucagcauggcccuuacggccugggc
gacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacggg
gagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccg
accccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggu
gaauacguucccgggccuuguacacaccgcccgucacgccaugggagcgg
gcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggc
ccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggc
uggauc
....<<<<..[.(((..>>>>.<<<<.<<<<<..<<<<<<<......<<.
......<<<..<<...........................>>>>>.....
.<<.......<<<<<<<...<<...<<..<....<<<.......<<<...
...>>>........>>>.....<<<<..<<........>>..>>>>...<
<.......>>...>..>>..>>.>>>>>>><<<..........<<<<<<<
.......>>>>>>>..........>>>..<<<<<<<<....>>>...>>>
>>.>>..<.<<............>.>>..<<<<<..>>>>>.......>>
......<<.<<<.....<<......>>...>>>>>.>.>>>>>>..<<<<
......<.<<.....>>>.....>>>>....<<<<<........<<<...
...>.>>..........>>>>>......<<<<..(....<<<<<......
...)..........>>>>>.>>>>..>>>>>>>>>...........<<((
.....<<<<...<<<.<<<<<..<<<<<<<<.........<<<<<<....
.>>>>>>.......>>>>>..>>>.>>>>>..........<...<<<<<<
<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........
...<......>.>>>>>>>..>...........>>>...>>>>....<<<
<<<...<<...<<<<.........>>>>...>>>>>>>>..........<
<<<<<..<<<<<.<<<<...>>>>.>>>>>...<<..))>>.....>>>>
>>.>>..........<<<<......>>>>.........))).].<.<..<
<<<<<<.....<<<<....<<<<<<<........<<........>>....
.......<<<............<......<.<............>>....
..................>........<<...<<<<.<..<.....<<<<
.<<<....>>>..<<<<......>>>>...>>>>........<<..<<.<
<....<....<.......>..>.....>>.>>..................
..........>>.......>...>.>...>>>.>>.........>>>...
....>>>>>>>......<<<.........<<...<<...<<.......>>
..>>.....>>.........>>>...........<<<<<<<........>
>>>>>>...........>>>>......<<<<<<..........>>>>>>.
...........>>>>>>>.>..>........<<...<<<<.<<<..<<.<
<<<..<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>..>>>
>.>>..>>>.>>>>....>>.........<<<<.<<<<....>>>>.>>>
>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6gzx Cryo-EM structure of the hibernating Thermus thermophilus 100S ribosome reveals a protein-mediated dimerization mechanism.
Resolution4.57 Å
Binding residue
(original residue number in PDB)		M1 R5 L6 R8 S11 K12 H13 H16 R18 A24 R25 R26 D29 K31 Y38 P41 R42 T45 W59 T67 T69 R71 R72 R75 F80 R81 Q82 E83 A84
Binding residue
(residue number reindexed from 1)		M1 R5 L6 R8 S11 K12 H13 H16 R18 A24 R25 R26 D29 K31 Y38 P41 R42 T45 W59 T67 T69 R71 R72 R75 F80 R81 Q82 E83 A84
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gzx, PDBe:6gzx, PDBj:6gzx
PDBsum6gzx
PubMed30301898
UniProtQ5SJH3|RS16_THET8 Small ribosomal subunit protein bS16 (Gene Name=rpsP)

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