Structure of PDB 6hcm Chain P1 Binding Site BS01

Receptor Information

>6hcm Chain P1 (length=136) Species: 9986 (Oryctolagus cuniculus)

SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Ligand information

>6hcm Chain A1 (length=1732)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggucaggcggcuuuggugac
ucuagauaaccucgggccgaucgcacgcccggcggcgacgacccauucga
acgucugcccuaucaacuuucgaugguagucgccgugccuaccaugguga
ccacgggugacggggaaucaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacuccc
gacccggggagguagugacgaaaaauaacaauacaggacucuuucgaggc
ccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauugg
agggcaagucuggugccagcagccgcgguaauuccagcuccaauagcgua
uauuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcggc
cguccccugccucucggcgccccggggcccgaagcguuuacuuugaaaaa
auuagaguguucaaagcaggccgccuggauaccgcagcuaggaauaaugg
aauaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauu
aagagggacggccgggggcauucguauugcgccgcuagaggugaaauucu
uggaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuu
cauuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucg
uaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauuccc
augacccgccgggcagcuuccgggaaaccaaagucuuuggguuccggggg
gaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccac
caggaguggagccugcggcuuaauuugacucaacacgggaaaccucaccc
ggcccggacacggacaggauugacagauugauagcucuuucucgauuccg
ugggugguggugcauggccguucuuaguugguggagcgauuugucugguu
aauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccc
ggucggcguaacuucuuagagggacaaguggcguucagccacccgagauu
gagcaauaacaggucugugaugcccuuagauguccggggcugcacgcgcg
cuacacugacuggcucagcgugugccuacccuacgccggcaggcgcgggu
aacccguugaaccccauucgugauggggaucggggauugcaauuauuccc
caugaacgaggaauucccaguaagugcgggucauaagcuugcguugauua
agucccugcccuuuguacacaccgcccgucgcuacuaccgauuggauggu
uuagugaggcccucggaucggccccgccggggugcccuggcggagcgcug
agaagacggucgaacuugacuaucuagaggaaguaaaagucguaacaagg
uuuccguaggugaaccugcggaaggaucauua

...<<<<<.{.((((>>>>><<<.<<<<<<.....<<..<......<<<.
<<<...<....<<....<<..........>>...>>.>.......<<...
.....<<<.<....<<....<<<<..........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>><<..<<<<<......((((.((.<<..<...>.>>....<.....
.>..>>>>>......>>...<<<<..<<<.>>>.>>>>..>.>>>...>>
..>.>>>.<<<....<<<....<<<<<<<.........>>>>>>>>>>..
....>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<.......
...>>>.>>...<<....>>.....>>>>>>.........<<<....<<<
.....>>>..>>>..>...>>.......<<<<<<<<<.<<......>>..
>>>>>>.>>>......<<..<...........>..>>.........<<<<
<((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>
>.>>>.........<..[[.....<.<<...<<<.<<....<<<.<<<..
>>>.>>>...........<.<<<.>>>>.........<<<<<<.<.....
..<<...<.......>.<<<<.>>>>...>>......>.>>>..>>>...
.......<<.<<<<<<<......)).))))..>>>>>>>.>>......>>
....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>.
.....>>>>>>>>..>>.......<<....>>...>>>>..>..>>>.>>
>...>>>...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>.
..>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<......
..>>>>>>>>>.>..>>>...<<..]]>>...>>.....>>>...>.<<<
......<<<......>>>....>>>..)))).}<<<<<.<<<<<<<...<
..<<<<<..<<<.<<<<<<......<<........>>..........<<<
<<......<<<<<........<<.<<<........>>>.>>......>>>
>>...<<.<<<..<<.<<<<<.....<<<.<<<<......>>...<<<..
....>>>...>>.>>>....<<<...<...<<<<..<<<<<<<<.<<<..
>>>..>>>>>>>>..>>>>..>.....<<<<<.....>>>>>........
>>>.....>>.>>>.....>>>>>>>.......>>>>>...>>.>>>>.>
>>.....<<.<<<................<<<.<<<<....>>>>.>>>.
.............>>>.>>............<<<<<..........>>>>
>...........>>>>>.....<<<<<<<<.......>>>>>>>>.....
.>....>>>>>>>>>>.>>.......<<.<..<<<<.<<....<<<<<<<
<.<<<..<<<<.<<...<<<<<.<<<<<<<<<..>>>>>>>>>...>>>>
>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>........
..<<<<<<<<....>>>>>>>>..........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6hcm ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
• Resolution: 6.8 Å
• Binding residue (original residue number in PDB): N38 D39 F41 H43 G49 K50 E51 T52 R55 G59 M60 D65 R66 E68 I135 S137 D138 T140 R141 G144 R146 R147 R149 R150
• Binding residue (residue number reindexed from 1): N23 D24 F26 H28 G34 K35 E36 T37 R40 G44 M45 D50 R51 E53 I120 S122 D123 T125 R126 G129 R131 R132 R134 R135

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Dec 2 21:03:04 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '6hcm', asym_id = 'P1', bs = 'BS01', title = 'ZNF598 Is a Quality Control Sensor of Collided Ribosomes.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='6hcm', asym_id='P1', bs='BS01', title='ZNF598 Is a Quality Control Sensor of Collided Ribosomes.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '6hcm', asym_id = 'P1'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='6hcm', asym_id='P1')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>