Structure of PDB 8uu9 Chain P Binding Site BS01

Receptor Information
>8uu9 Chain P (length=123) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GYRKLGRTSSQRKALLRDLATDLIVHERIETTEARAKEIRKVVEKLITSG
KKGDLHARRQAAAFIRHEVVEVVQVKNRPVYALQKLFDDVAPRYAERQGG
YTRILKKGPRRGDGAPMVIIELV
Ligand information
>8uu9 Chain A (length=2899) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaaga
aggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguuga
uccagagauuuccgaaugggggaacccacuaucuuuagucggauaguauc
cuuacgugaauacauagcgugaggaaggcagacccagggaacugaaacau
cuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggcg
agcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguuguag
gacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugga
aaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccuc
cagaguggauccugaguacgacggaacacgugaaauuccgucggaauccg
ggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaacc
aguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacagu
uccugaaaccgugugccuacaaguaguuagagcccguuaaugggugauag
cgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguuaa
gcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaag
uaacaggucguagacccgaaaccaggugaucuacccauguccaggaugaa
gguaagguaauacuuacuggagguccgaacccacgcacguugaaaagugc
ggggaugagguguggguagcggagaaauuccaaucgaacuuggagauagc
ugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucaug
gagguagagcacuguuuggacuaggggaccgaauucagauaaacuccgaa
ugccauguacuuauacucgggagucagacugcgagugauaagauccguag
ucgaaagggaaacagcccagaccaccaguuaagguccccaaauauauguu
aaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuaga
agcagccaccauugaaagagugcguaauagcucacuggucgagugacccc
gcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaac
cuagguucgugguaggagagcguucuaagggcggugaagucagaccggaa
ggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaaga
agggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcuc
guccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggcg
auggacaacagguagagauuccuguaccagugcuaauuguuuaaccgaug
gggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaag
cagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugu
gauggggaagacggaaguuccugauuucacgcugucaagaaaagccucua
ggaagaguaguacugcccguaccgcaaaccgacacagguagaugaggaga
gaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaauga
ccccguaacuucgggagaaggggugcucuauuagggugcaagcccgagag
agccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucucu
gcaaaaccguaaggugacguauaggggcugacgccugcccggugcuggaa
gguuaagaggagugcuuagcuucggcgaagguacgaauugaagccccagu
aaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucg
gguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucucaa
cgagagacucggugaaauuauaguaccugugaagaugcagguuacccgcg
acaggacggaaagaccccguggagcuuuacugcaaccugauauggaaugu
uuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcuag
cauacgaggaggcaauggugggauacuacccuggcuguaugaccauucua
acccgccacgcuaagcgcguggggagacagugucaggugggcaguuugac
uggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccuca
gaauggauggaaaucauucgcagaguguaaaggcacaagggagcuugacu
gcgagacugacaagucgagcagggacgaaagucgggcuuagugauccggu
gguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgggga
uaacaggcuuaucucccccaagaguccacaucgacggggagguuuggcac
cucgaugucggcucgucgcauccuggggcuguagucggucccaaggguug
ggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucguga
gacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagcug
uccuuaguacgagaggaccgggauggacacaccgcugguguaccaguugu
uccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcuga
aagcaucuaagcgugaagccccccucaagaugagauuucccauuucuucg
gaaaguaagaucccugaaagaugaucagguagauagguuuggaguggaag
uguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<....
..>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>>
>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<
<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...........
....<<....>>....]].........<<<<....>>>>...........
..}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.......>>...>>>...<<....>>..<<<<.....>>>>......>
>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....
<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>
>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>
.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<<
<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>...
..>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>
>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.
..........<<..<<<<<<<<<<.......<<<<<.<<...<<<<....
...>>>>...>>.........<<......>>...>>>>>...>>>>>>>>
>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<
<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....
>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<
<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<...
..>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>.
..>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...<
<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<
<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>
...>>............>>>>>...>>>...>>>>........>>>>>..
>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<..
...>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<
<<<<....<<..>>.....>>>>><<<<<....<<<<....>>>>...>>
>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<
.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..
<<<<..<<...<<<<<<.<<<..>>>..>>>>>>...>>..>>>>>>>>>
..>>>>><<<<<<.......>>>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.
<<<<<<.<<<.<.........<<<<<..<<<.......<<<<<<<....>
>>>>>>....>>>............>>>>>>.>>>.>>>>>>.>>>>>..
..<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<
<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...
<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...<<
<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<
<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>..
.....<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>
.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<
<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....
>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<
<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<
<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<..
.........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<..>
>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8uu9 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G2 Y3 R4 K5 S10 S11 Q12 R13 K14 L16 R18 D23 T32 T33 A35 K38 E39 E45 T49 L56 H57 R59 R60 R67 H68 Y93 G111 G112 T114 R122 R123 G124 D125
Binding residue
(residue number reindexed from 1)		G1 Y2 R3 K4 S9 S10 Q11 R12 K13 L15 R17 D22 T31 T32 A34 K37 E38 E44 T48 L55 H56 R58 R59 R66 H67 Y81 G99 G100 T102 R110 R111 G112 D113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uu9, PDBe:8uu9, PDBj:8uu9
PDBsum8uu9
PubMed38407413
UniProtA0A0U4VSW3

[Back to BioLiP]