Structure of PDB 8uu8 Chain P Binding Site BS01

Receptor Information
>8uu8 Chain P (length=122) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YRKLGRTSSQRKALLRDLATDLIVHERIETTEARAKEIRKVVEKLITSGK
KGDLHARRQAAAFIRHEVVEVVQVKNRPVYALQKLFDDVAPRYAERQGGY
TRILKKGPRRGDGAPMVIIELV
Ligand information
>8uu8 Chain A (length=2901) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuaggguaccgaauucagauaaacuccga
augccauguacuuauacucgggagucagacugcgagugauaagauccgua
gucgaaagggaaacagcccagaccaccaguuaagguccccaaauauaugu
uaaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuag
aagcagccaccauugaaagagugcguaauagcucacuggucgagugaccc
cgcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaa
ccuagguucgugguaggagagcguucuaagggcggugaagucagaccgga
aggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaag
aagggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcu
cguccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggc
gauggacaacagguagagauuccuguaccagugcuaauuguuuaaccgau
ggggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaa
gcagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcug
ugauggggaaguacggaaguuccugauuucacgcugucaagaaaagccuc
uaggaagaguaguacugcccguaccgcaaaccgacacagguagaugagga
gagaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaau
gaccccguaacuucgggagaaggggugcucuauuagggugcaagcccgag
agagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucu
cugcaaaaccguaaggugacguauaggggcugacgccugcccggugcugg
aagguuaagaggagugcuuagcuucggcgaagguacgaauugaagcccca
guaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugu
cggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucuc
aacgagagacucggugaaauuauaguaccugugaagaugcagguuacccg
cgacaggacggaaagaccccguggagcuuuacugcaaccugauauggaau
guuuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcu
agcauacgaggaggcaauggugggauacuacccuggcuguaugaccauuc
uaacccgccacgcuaagcgcguggggagacagugucaggugggcaguuug
acuggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccu
cagaauggauggaaaucauucgcagaguguaaaggcacaagggagcuuga
cugcgagacugacaagucgagcagggacgaaagucgggcuuagugauccg
gugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccggg
gauaacaggcuuaucucccccaagaguccacaucgacggggagguuuggc
accucgaugucggcucgucgcauccuggggcuguagucggucccaagggu
ugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucgu
gagacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagc
uguccuuaguacgagaggaccgggauggacacaccgcugguguaccaguu
guuccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcu
gaaagcaucuaagcgugaagccccccucaagaugagauuucccauuucuu
cggaaaguaagaucccugaaagaugaucagguagauagguuuggagugga
aguguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaac
c
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>..
...>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>
>>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<
...........<<..<<<<<<<<<<<......<<<<<.<<<..<<<<...
....>>>>..>>>.........<<......>>...>>>>>..>>>>>>>>
>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<
<<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<...
.>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<
<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<..
...>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>
...>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...
<<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..
<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>
>...>>.............>>>>>...>>>...>>>>........>>>>>
..>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<
.....>>>>..>>>>..<<<<....<<<<<<<<.<<.........<....
.<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>...
>>>>>............<<<<<<<<<..<<<.........>>>..<<<<<
<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<
..<<<<..<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>
>>..>>>>><<<<<<.......>>>>>>........<...........<<
<<<.......>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.
>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<
<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<
<.<<<<<<.<<<...........<<<<<..<<<.......<<<<<<<...
.>>>>>>>....>>>............>>>>>..>>>.>>>>>>.>>>>>
....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<
<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...
<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<
<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>
.......<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>
.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.
<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<
<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<
<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<
...........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<..
..>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<...
.<<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uu8 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
Y3 R4 K5 G7 S10 S11 Q12 R13 D23 I30 E31 T33 A35 K42 E45 K46 T49 L56 H57 R59 R60 R67 H68 R90 Y93 R109 G111 G112 T114 R115 R122 G124 D125
Binding residue
(residue number reindexed from 1)
Y1 R2 K3 G5 S8 S9 Q10 R11 D21 I28 E29 T31 A33 K40 E43 K44 T47 L54 H55 R57 R58 R65 H66 R77 Y80 R96 G98 G99 T101 R102 R109 G111 D112
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uu8, PDBe:8uu8, PDBj:8uu8
PDBsum8uu8
PubMed38407413
UniProtA0A0U4VSW3

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