Structure of PDB 8tj5 Chain P Binding Site BS01

Receptor Information
>8tj5 Chain P (length=1641) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FTHVANFMNDAAADVSAVDAKQLAQIRQFLKANKTNLIESLNTIRQNVTS
SGDHNKLRSTIANLLQINVDNDPFFAQSEDLSHAVEFFMSERSSRLHIVY
SLLVNPDIDLETYSFIDNDRFNVVGKLISIISSVIQNYDIITASSLAHDY
NNDQDMFTIVSLVQLKKFSDLKFILQILQILNLMILNTKVPVDIVNQWFL
QYQNQFVEFCRNINSTDKSIDTSSLQLYKFQNFQDLSYLSETLISRISSL
FTITTILILGLNTSIAQFDIQSPLYMDTETFDTVNSALENDVATNIVNED
PIFHPMIHYSWSFILYYRRALQSSESFDDSDITKFALFAESHDVLQKLNT
LSEILSFDPVYTTVITVFLEFSLNFIPITASTSRVFAKIISKAPEQFIEN
FLTNDTFEKKLSIIKAKLPLLNESLIPLINLALIDTEFANFELKDICSFA
VTKSSLNDLDYDLIADTITNSSSSSDIIVPDLIELKSDLLVAPPLENENS
NCLLSIPKSTKGKILTIKQQQQQQQQQNGQQPPTTSNLIIFLYKFNGWSL
VGRILQNLLHSYMEKGTQLDDLQHELMISIIKLVTNVVDPKTSIEKSSEI
LSYLSNSLDTSASTINGASIIQVIFEIFEISLQRKDYTSIVQCCEFMTML
TPNYLHLVSSYLNKSDLLDKYGKTGLSNMILGSVELSTGDYTFTIQLLKL
TKVFIRESLSLKNIHISKRSKIDIINKLILHAIHIFESYYNWKYNNFLQK
FEIAFHLTLIFYDVLHDVFTINPHQKDQLIISSSANKLLQLFLTPMDSID
LAPNTLTNILISPLNTTTKILGDKILGNLYSKVMNNSFKLCTLLIAIRGS
NRDLKPSNLEKLLFINSSKLVDVYTLPSYVHFKVQIIELLSYLVEAPWND
DYPFLLSFLGEAKSMAFLKEVLSDLSSPVQDWNLLRSLYIFFTTLLESKQ
DGLSILFLTGQFASNKKINDESSIDKKSSILTVLQKNSLLLDSTPEEVSC
KLLETITYVLNTWTNSKIFIKDPKFVNSLLAKLKDSKKLFQKKENLTRDE
TVSLIKKYKLISRIVEIFALCIYNSTDSNSEILNFLNQEDLFELVHHFFQ
IDGFNKTFHDELNLKFKEKWPSLELQSFQKIPLSRINENENFGYDIPLLD
IVLKADRSWNEPSKSQTNFKEEITDASLNLQYVNYEISTAKAWGALITTF
VKRSTVPLNDGFVDLVEHFLKLNIDFGSDKQMFTQIYLERIELSFYILYS
FKLSGKLLKEEKIIELMNKIFTIFKSGEIDFIKNIGKSLKNNFYRPLLRS
VLVLLELVSSGDRFIELISDQLLEFFELVFSKGVYLILSEILCQINKCST
RGLSTDHTTQIVNLEDNTQDLLLLLSLFKKITNVNPSKNFNVILASSLNE
VGTLKVILNLYSSAHLIRINDEPILGQITLTFISELCSIEPIAAKLINSG
LYSVLLESPLSVAIQQGDIKPEFSPRLHNIWSNGLLSIVLLLLSQFGIKV
LPETCLFVSYFGKQIKSTIYNWGDNKLAVSSSLIKETNQLVLLQKMLNLL
NYQELFIQPKNSDDQQEAVELVIGLDSEHDKKRLSAALSKFLTHPKYLNS
RIIPTTLEEQQQLEDESSRLEFVKGISRDIKALQDSLFKDV
Ligand information
>8tj5 Chain i (length=22) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8tj5 Implications of a multiscale structure of the yeast nuclear pore complex.
Resolution6.6 Å
Binding residue
(original residue number in PDB)		E354 F389 K423
Binding residue
(residue number reindexed from 1)		E340 F375 K409
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0017056 structural constituent of nuclear pore
Biological Process
GO:0006405 RNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006913 nucleocytoplasmic transport
GO:0006999 nuclear pore organization
GO:0015031 protein transport
GO:0031990 mRNA export from nucleus in response to heat stress
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0044611 nuclear pore inner ring

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8tj5, PDBe:8tj5, PDBj:8tj5
PDBsum8tj5
PubMed37738963
UniProtP52593|NU188_YEAST Nucleoporin NUP188 (Gene Name=NUP188)

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