Structure of PDB 8etj Chain P Binding Site BS01

Receptor Information
>8etj Chain P (length=156) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSASPALETKCAKARGAYLRTHFKNSREVAFTINGMSLKKAFIFLDNVKE
HKQAVPFRRFNGGVGRTAQGKEFGVTQARWPVKSVKFFYDLLKNAEANAE
AKGLDMDKLIIKHVQVNAAPKQLSSPSHIEIIVAEEESRVSLKQGAKARN
LAARKA
Ligand information
>8etj Chain 1 (length=1817) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaaugggugguaaauuucauc
uaaagcuaaauauuggcgagagaccgauagcgaacaaguagagugaucga
aagaugaaaagaacuuugaaaagagaguuaaauaguacgugaaauugcug
aaagggaagcauuggaaaucaggucagcaucaguuuucgggggcggaaaa
agaauaagggaagguggcuuuccgggaguguuuauagcccuuguuguaau
acguccacuggggacugaggacugcggcuucgugccaaggaugcugacau
aaugguuuucaauggcccgucuacacggaccaaggagucuagcaucuaug
cgaguguuugggugaugaaaacccauccgcgaaaugaaagugaaugcagg
ugggaacgcccuuguggcgugcaccaucgaccgacccggaaguauggaag
gguuugaguaagagcauagcuguugggacccgaaagauggugaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaaacucagauc
aguuuuaugaguauguaaaaugagaguuucuagugggccauuuuugguaa
gcagaacuggcgaugcgggaugaaccgaacgugagguuaaggugccggaa
uguacgcucaucagaagaaaagguguuaguucaucuagacagcaggacgg
uggccauggaagucggaauccgcuaaggaguguguaacaacucaccugcc
gaaugaacuagcccugaaaauggauggcgcuuaagcguacuacccauacc
ucaccgucuggguugaagcucagacgaguaggcaggcguggagguuugug
acgaagccuugggcgugagccugggucgaacagccucuagugcagaucuu
gguggaaguagcauucaaaugagaacuuugaagacugaaguggggaaagg
uuccaugugaacagcaguuggacauggguuccaaggugaacagccucuag
uugauagaacaauguagauaagggaagucggcaaaaugccacugucccua
ucuacuaucuagcgaaaccacagccuggggaacgggccaggcaaaaucag
cggggcuuguggcagucaagcggcgacauugcuuuccuaucauaccgaag
cagaauucgguaagcguuggacccacuaauagggacuacugaugaagugu
cgucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauc
auugguauuugcggcugccugacaaggcaaugccgcggagcuaucaucug
cuggauaacggcugaacgccucuaagccagaauccgugccagaaagcgac
gauuuuuugguccgcaugauuuauauguauaaaaauagagguaggcuacu
cuccuguaucguagaagaugggcgaugguugaugaaacggaaguguuuua
uugacuuguccaugaaauuccaaucuugugcggaaucgaauccauugcau
acgacuuuaauguggaacgggguauuguaagcagcugcugagauuaagcc
uuuguucccaagauuug
.........................<<<<<........>>>>>.......
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<..
......<<.<<<<<<<.......>>>>>>>.>>........>....<<<<
<.<<<<<..<<<<<...<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>...>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<<......>>>>>
>..>>>..................................<<....>>..
.............<<<<....>>>>.........................
.........<<<<<<<<<<<<.<<<<<<<.<<<<<<<<<<<<<<<.....
...<<<<<<<......<.<<<<..>>>>..>......>>>>>>>......
.>>>>>.>>>>>>>>>>........<<<.....>>>.....>>>>>>>..
..>>>>>>>>>>>>..<<<<....>>>><<<<<<....<<<<<<.<<<<<
<..<<<..<<<<<.......>>>>>..>>>...<<....>>.......<<
<<<..<<<<<.....>>>>>...>>>>>.<<<<<<<<....<<>>....>
>>.>>>.>>....>>>>>>.>>>>>>..<<.<...<<<<<<..>>>>>>.
.....>.>>..<<<<<<.......<<....>>...<<<<<<<<<<...<<
<.<<<<<<<....>>>>>>>>>>>>>>>>>>.>>..<<<<.<<.<<....
.>>.>>.>>>>....<<<......>>>...<<<<<<<...<<<(((....
.<<<<<<.....<<......<<<.<<<<<<<<<<.......<<<<<.<<.
...<<.........>>....>>.........<<......>>...>>>>>.
..>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>...>>>
>>>><<<<<<<<<....>>>>>>>>>....>>>>>>..<<<<<<<<.<<.
.....<<<<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>
>>><<.....<<.<<<<<<.......>>>>>><<<<<....<<<......
..<<<<<....<<.....>>..>>>>>..>>>.<<<<.....>>>>.>>>
>>..<<<<.....<<<<<<<.<<.........<.........>..>>.>>
>>>>>..>>>>>>....>>....<<<<<........>>>>>....<<<<<
..<.......<<<<<<...<<.>>...>>>>>><<<<<..<.<<<<<<<.
.....>>>>>>>...>.<<<..>>>.....>>>>>.>.>>>>>.....<<
<<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<.
..<<<<....<<<<<<<<<<....>>>>>..>>>>>...>>>>..>>>>>
.<<<<....<<<<...........>>>>....>>>>.>>>>....>>>>>
>>>.....<.<<<..<.<..........<<.......<<<<..<..>..>
>>>....>>........<<<<<....<<<<<<<<<<<<......>>>>>>
>>>>>>..>>>>>.............>.>..>>>.>.<<<<<.<......
.......>.....<<<<<<<<<.<<<....<<<..>>>...>>>....>>
>>.>>>>>...>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8etj Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K16 R18 Y21 R23 H25 F26 K27 R30 K43 K55 R62 F63 G65 G68 R69 A71 Q72 K74 T79 Q80 R82 W83 P84 V85 K86 N97 A100 N101 H116 Q118 V119 S141 R166 L169 K170 A173 K174 R176 R181
Binding residue
(residue number reindexed from 1)		K13 R15 Y18 R20 H22 F23 K24 R27 K40 K52 R59 F60 G62 G65 R66 A68 Q69 K71 T76 Q77 R79 W80 P81 V82 K83 N94 A97 N98 H113 Q115 V116 S124 R139 L142 K143 A146 K147 R149 R154
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8etj, PDBe:8etj, PDBj:8etj
PDBsum8etj
PubMed36423630
UniProtO14339|RL17A_SCHPO Large ribosomal subunit protein uL22A (Gene Name=rpl1701)

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