Structure of PDB 8a3w Chain P Binding Site BS01

Receptor Information
>8a3w Chain P (length=196) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVDLTGISKKSRVIRHHTYSTNPYIKLLIKLYKFLAKRTSSGFNKVVYQR
LIKSRSNRAPISLSRIAVVMKRKAVFTAKSKAAPIAVVVGDVLDDVRMAR
IPAMRVCALRFSKSARQSIVAAGGECLTFDQLAMIAPTGKNTYLLRGRKS
GRESVRHFGASGVPGSHSKPYATNRGKETKRGRRTGRSYKRKAFRH
Ligand information
>8a3w Chain 2 (length=947) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaauugccaacucagaa
cugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugau
gcauccaagugguguauaucgcaaacugauuucugcccagugcucuguca
acgugacgagauucaccgacgcgcggguaaacggcgggcucucuuaaggu
agccaaaugccucgucuuccaauuagagacgcgcaugaauggauuaauga
gauucccucugucccgaguuacuaucuagcgaaacgacagucaagggaac
ggacuugaagggcuaagcggggaaagaagacccuguugaguuugacucca
gucuggcucugugcgguucacuuaucgaaugaagagaccaauggguuuag
cguagucuggcuaugcaccgucuagguuccgugcuguaaacugaaccaac
gggaguuccggagucuuguuucgagacaucugccagauggggaguuuggc
uggggcggcauaucuguuacacgacaacgcagguguccuaaggcgagcuc
agugggaucucacguagaacacaagcguaaaagcuugcuugauuaacgau
uuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaaggcuu
gauccuucgaugucggcucuuccuaaccuagcggcuaaggguuggauugu
ucacccacugacagggaacgugagcuggguuuagaccgucgugagacagg
uugguuuuacccuacuuagcuggaaauugcgagaaaaauccguaagc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.
>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<...
.<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<<..
..<<<<......>>>>....>>..>>>>..>>>>><<....>>.......
.<...........<<<<<.......>>>>>.....>.....>>....>>.
>>>>>>>..>..>>.>>>>>>>>.>>>>............<<<<<.....
...>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.
<<<<<<<...<<<.<.>.>>>...<<<<<.....<<<<...........<
.<<<.........>>>.>...............................<
<<<...>>>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<..>>>>>.....<<......>>....>>>>>>>...<<...<<<
<<.......>>>>>..>>.<<<....>>>.>>.........<<<<<..<<
<.......>>>..>>>>>..........>>>>..>>>>>>.....<<.<.
>.>.>.......<<<<<.<<<<<<..<<<<<<.>>>..>>>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>.>>>>>>>..........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)		P165 R185 S189 K193 H197
Binding residue
(residue number reindexed from 1)		P164 R184 S188 K192 H196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4QG98|RL18_LEIMA Large ribosomal subunit protein eL18 (Gene Name=RPL18-A)

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