Structure of PDB 7sae Chain P Binding Site BS01

Receptor Information

>7sae Chain P (length=114) Species: 1423 (Bacillus subtilis)

QKLIEDITKEQLRTDLPAFRPGDTLRVHVKVVEGNRERIQIFEGVVIKRR
GGGISETFTVRKISYGVGVERTFPVHTPKIAKIEVVRYGKVRRAKLYYLR
ELRGKAARIKEIRR

Ligand information

>7sae Chain A (length=2434)

uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacgaacaccgauaugcuucggggagcuguaagcaagcuuuga
uccggagauuuccgaauggggaaacccaccacucguaauggagugguauc
cauaucugaauucauaggauaugagaaggcagacccggggaacugaaaca
ucuaaguacccggaggaagagaaagcaaaugcgauucccugaguagcggc
gagcgaaacgggaucagcccaaaccaagaggcuugccucuugggguugua
ggacacucuguacggaguuacaaaggaacgagguagaugaagaggucugg
aaaggcccgccauaggagguaacagcccuguagucaaaacuucguucucu
ccugaguggauccugaguacggcggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaagag
auccugaaaccgugugccuacaaguagucagagcccguuaacgggugaug
gcgugccuuuuguagaaugaaccggcgaguuacgaucucgugcaagguua
agcagaagaugcggagccgcagcgaaagcgagucugaauagggcgcauga
guacguggucguagacccgaaaccaggugaucuacccauguccaggguga
aguucagguaacacugaauggaggcccgaacccacgcacguugaaaagug
cggggaugagguguggguaggggugaaaugccaaucgaaccuggagauag
cugguucucuccgaaauagcuuuagggcuagccucaagguaagagucuug
gagguagagcacugauuggacuaggaauucagucaaacuccgaaugccaa
ugacuuauccuugggagucagacugcgagugauaagauccguagucgaaa
gggaaacagcccagaccgccagcuaaggucccaaaguauacguuaagugg
aaaaggauguggaguugacucugcgccgaaaauguaccggggcuaaacgu
aucaccgaagcugcggacuguucuucgaacagugguaggagagcguucua
agggcugugaagccagaccggaaggacugguggagcgcuuagaagugaga
augccgguaugaguagcgaaagaggggugagaauccccuccaccgaaugc
cuaagguuuccugaggaaggcucguccgcucaggguuagucgggaccuaa
gccgaggccgaaaggcguaggcgauggacaacagguugauauuccuguac
caccuccucaccauuugagcaauggggggacgcaggaggauaggguaagc
gcgguauuggauauccgcguccaagcaguuaggcugggaaauaggcaaau
ccguuucccauaagccugagcugugauggcgagcgaaauauaguagcgaa
guuccugauuccacacugccaagaaaagccucuagcgaggugagaggugc
ccguaccgcaaaccgacacagguaggcgaggagagaauccuaaggugauc
gagagaacucucguuaaggaacucggcaaaaugaccccguaacuucggga
gaaggggugcucuguuagggugcaagcccgagagagccgcagugaauagg
cccaggcgacuguuuagcaaaaacacaggucucugcgaagccguaaggcg
aaguauaggggcugacgccuaggcgcaacgaucugggcacugucucaacg
agagacucggugaaauuauaguaccugugaagaugcagguuacccgcgac
aggacggaaagaccccguggagcuuuacugcagccugauauugaaugucc
uucuaacccgccgcccuuaucgggcggggagacagugucaggugggcagu
uugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguuc
ccucagaaugguuggaaaucauucgcagaguguaaaggcacaagggagcu
ugacugcgagaccuacaagucgagcagggacgaaagucgggcuuagugau
ccggugguuccgcauggaagggccaucgcucaacggauaaaagcuacccc
gguccgucgcgggcgcaggaaauuugagaggagcuguccuuaguacgaga
ggaccgggauggacgcaccgcugguguaccaguuguucugccaagggcau
cgcuggguagcuaugugcggacgggauaagugcugaaagcaucuaagcau
gaagccccccucaagaugagauuucccauuccgcaaggaaguaagauccc
ugaaagaugaucagguugauaggucugagguggaaguguggcgacacaug
gagcugacagauacuaaucgaucgaggacuuaac

<<<<<<......<<<<<<<<<<<....<<<..<<<<<<<<<<<<<.....
.<<<<<<.....((.>>>.....<<<<<<<..<<<)).....>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<.....
.>......>>>>>.>.........<<....>>...<<<<......<<...
..>>.....>>>>...<<<....<<<<<<<<<..>>>>>>>>>......<
<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>>>>
>>.>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..((((>>>>>..>>>......>>.>>>>>>>.>>..........
.....<<....>>....>>.........<<<<....>>>>..........
...>....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<..
.<<<.....>>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>.>>>>>>>..<<.....<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......
..>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<
<.....<<<...<<<...<.........>...>>>..>>.>.....>>>>
.>>>>>..>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>....
<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.......
....<<...<<<<<<..>>>>>>..>>...........))).....>>>>
>>.>>>...>>>>>>><<<<<<<...>>>>>>>....>>>>>><.<<<<<
<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>..>...
..>>>>>><......<<....<<<<<<.......>>>>>><<<<....<<
<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<...
<<<...<<<....>>>...>>>...>>...<<<<<........>>>>>))
<<<<<.<<<<<<......<<...<<<<....<<<<..<<<..<<<.<.<<
<.<...[.[....>.>>>.<<..<....<.<<<<.<<<<<<<.<<.....
>>>>>>>>>....>>>>..>...>...>><..<<...........>>...
>>.>>>...>>>...>>>>.........>>>>..>>..>>>>>>>>>>>>
>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<
<<<....<<<<<<<<.<<<..............<<<<<....<<..>>..
...>>>>><<<<<....<<<<....>>>>...>>>>>............<
<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>>>.
......>>>>>>>..<<<<..>>>>...>>.>>>>>>>....>>>.>>>>
>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<
.<<................<<<<<..<<<<..<<<<<<<<<.<<<.....
>>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>...>>>>
..<<<.......>>><<<<<<...........>>>>>>..<<...<<<<<
.<<...<<<.<.......>.>>>......<<...(((>>....>>>>>>>
...<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))......
.<<<<<<<.<<..))))..>>>>>>>>>.............>>>>...>.
...>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<..........
.....>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.].]>>>>>>.
.>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>>>>
....>>>.>>>>.......>>>>>>>..<<<<....>>>>....<<<<<<
<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>.
..>>>..>>>>>.>>>...>>>>....>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7sae RbgA ensures the correct timing in the maturation of the 50S subunits functional sites.
• Resolution: 3.0 Å
• Binding residue (original residue number in PDB): R24 R54 S59 R96 R97 A98 K99 Y101
• Binding residue (residue number reindexed from 1): R20 R50 S55 R92 R93 A94 K95 Y97

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7sae, PDBe:7sae, PDBj:7sae
• PDBsum: 7sae
• PubMed: 35141754
• UniProt: O31742|RL19_BACSU Large ribosomal subunit protein bL19 (Gene Name=rplS)