Structure of PDB 7rm4 Chain P Binding Site BS01

Receptor Information
>7rm4 Chain P (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7rm4 T cell receptors employ diverse strategies to target a p53 cancer neoantigen.
Resolution3.33 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 R65 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E63 R65 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7rm4, PDBe:7rm4, PDBj:7rm4
PDBsum7rm4
PubMed35124005
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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