Structure of PDB 7r72 Chain P Binding Site BS01

Receptor Information
>7r72 Chain P (length=51) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVSFKNTRETQVLDHFNSSIGRKARWPAKSVKFRRRTYRAHGRINKYESS
P
Ligand information
>7r72 Chain 1 (length=641) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augccugaauagggugaagccagaggaaacucugguggaggcucgcgaau
uuggguauaguagcaaauauucaaaugagaacuuugaagacugaaguggg
gaaagguuccacgucaacagcaguuggacguggguuagucgauccuaaga
gaugguuucaaaggccugauucaggccaccaucgaaagggaauccgguua
agauuccggaaccuggauauggauucuucacgguaacguaacugaaugug
gagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcu
uaucaccccggaauugguuuauccggagauggggucuuauggcuggaaga
ggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauc
cacaggaaggaauaguuuucaugccaggucguacugucuccaaggugaac
agccucuaguugauagaauccguaacuucgggauaaggauuggcucuaag
ggucggguagugagggccuuggucacggccuuggcuugcuacaauuaacg
aucaacuuagaacugguacggacaauaucuagcgaggcugucugaucagg
cauugcguaagcaguagaguagccguuacgaucugcugaga
<<<<<<<<...<<<....<<<<<<<....>>>>>>>.....>>>......
>>>>>>>>....<<.....<<<<<<.......>>>>>><<<<.....<<<
<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<
............<<<<<<...>>>>>>....>>....>>...<<<<<...
.....>>>>>))<<<<.<<<<<<......<<<....>>>.......<<<<
<<...<<<<.<<<<<<<.<<<<<<<<<<..(((..>>>>>><...<<<<<
....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....>
<<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>
>>>>............>>.>>>>>>>>>>>>..>>.>>>>>.<<<<....
.>>>>..>>>>..<<<<.<<<<<<.<<<<.....................
<<<<<.<<<<<<<<..<<..<<<<..>>>>..>>>>>>>>>>......>>
>>>......>>>...>>>>>>>.....>>>>>>...<<<<<<<))).>>>
>>..>>....<<<<....<<.......>>...>>>>.....
Receptor-Ligand Complex Structure
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PDB7r72 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		S25 K27 N28 F63 S65 G68 R82 W83 P84 K86 R127 T129 Y139 E140 S141
Binding residue
(residue number reindexed from 1)		S3 K5 N6 F16 S18 G21 R25 W26 P27 K29 R35 T37 Y47 E48 S49
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r72, PDBe:7r72, PDBj:7r72
PDBsum7r72
PubMed36482249
UniProtP05740|RL17A_YEAST Large ribosomal subunit protein uL22A (Gene Name=RPL17A)

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