Structure of PDB 7ohy Chain P Binding Site BS01

Receptor Information
>7ohy Chain P (length=126) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLEQVLDHQRAIP
FRRFNRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLY
VSHIQVNQAPKESSPSHIELVVTEKE
Ligand information
>7ohy Chain 1 (length=1689) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuaauaucaauaag
cggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcg
gcaaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauu
uggagagggcacuuuggggccguuccuugucuauguuccuuggaacagga
cgucauagagggugagaaucccguguggcgaggagugcgguucuuuguaa
agugccuucgaagagucgaguuguuugggaaugcagcucuaagugggugg
uuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacag
ugauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaa
auuguugaaagggaagggcauuugaucagacaugguguuuugugcccucu
gcuuaggggaaucucgcauuucacugggccagcaucaguuuugguggcag
gauaaauccauaggaauguagcuugccucgguaaguauuauagccugugg
gaauacugccagcugggacugaggacugcgacguaagucaaggaugcugg
cauaaugguuauaugccgcccgucuugaaacacggaccaaggagucuaac
gucuaugcgaguguuuggguguaaaacccauacgcguaauggugaacgua
gguuggggccucgcaagaggugcacaaucgaccgauccuggauggauuug
guaagagcauagcuguugggacccgaaagauggugaaaaccaucuaguac
ugguuccugccgaaguuucccucaggauagcagaagcucguaucaguuuu
auuaagaaugaagagcuuuuagugggccauuuuugguaagcagaacuggc
gaugcgggaugaaccgaacguagaguuaaggugccggaauacacgcucau
cagaccaaaagguguuaguucaucuagacagccggacgguggccauggaa
gucggaauccgcuaaggaguguguaacaacucaccggccgaaugaacuag
cccuguggcgcucaagcguguuaccuauacucuaccgucaggguugauug
augcccugacgaguaggcaggcguggaggucagugacgaagccuagaccg
uaaggucgggucgaacggccucuagugcagaucuuggugguaguagcagc
gaaaccacagccaagggacgggcuuggcagaaucagcgggcagucgcgac
auugcuauaccgaagcagaauucgguaacccuacugaugaauguuaccgc
aauaguaauugaacuuaguacgagaggaacaguucauucggauaauuggu
uuuugcggcugucugaucaggcagccgcgaagcuaccauccgcuggauua
uggcugaacgccucuaagucagaauccaugcuagaacgcggugauuucuu
ugcuccacacaauauagauggauacgaauaaggcguccuuguggcgucgc
ugaaccauagcaggcuagcaacggugcacuuggcggaaaggccuugggug
cuugcuggcgaauugcaaugucauuuugcguggggauaaaucauuuguau
acgacuuagauguacaacgggguauuguaagcaguagaguagccuuguug
uuacgaucugcugagauuaaccuuuguugucugauuugu
...........................<<<<<.....<...>......>>
>>>...........<<....>>..<<<<<......<<.....>>.....>
>>>>..<<<...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<<<<<.<<<<<<<<<<<<<<<<<.....<<<<......>>>>
.((......<<<.....))>>>....>>>>>>>>>..>>>>>>>.....>
>>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<
..>>>>>>..>>>..................................<<.
...>>...............<<<......>>>..................
................<<<<<.<<<<<......<<<<...<<<<.<<<..
......>>>.....>>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<
.....<<<<<<<<<......<<<<<......>>>>>.......>>>>>>>
.>.>.>>>>>.>>>>>>>>>>........<<<....>>>.....>>>>>>
>.....>>>>>.>>>>>..<<<<........>>>><<<<<<....<<<<<
<.<<<<<<..<<<...<<<<.....>>>>...>>>...<<.>>.......
<<<<<..<<<<<....>>>>>...>>>>>.<<<<<<<<.....>>>>>.>
>>....>>>>>>.>>>>>>..<<.<...<<<<<<....>>>>>>.....>
.>>..<<<<<<......<........>..<<<<<<<<<....<<<.<<<<
<.>>>.>>>>>..>>>>>>>.>>..<<<<.<.<<<.....>>>.>.>>>>
....<<<......>>>...<<<<<<<..<<<<(((.....<<<<<<....
.<<......<<<.<<<<<<<<<<.......<<<<<.<<<...<<......
...>>...>>>.........<<......>>...>>>>>...>>>>>>>>>
>>>>..))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<......
..>>>>>>>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<.
...>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<.....<<.>>
....>>....<<<<<.......>>>>>....<<<<<..<<<<<.......
.>>>>>.<<<<<<<......>>>>>>>......>>>>>....<<<<<<<<
..<<<<.<.<<<<<<...............>>>>>>.><<<<<...<<<<
....<<<<<<............>>>>>>...>>>>..>>>>>.<<<<...
<<<<<...........>>>>>...>>>>.>>>>....>>>>>>>>.....
..<<<<<<.<<<.<<....<<..........<<<<<<.....>>>>>>..
....>>.......<<<<<<...<<<<<.<..<<<......>>>..>.>>>
>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<......
.......>.....<<<<<<<<<.<<<......<<................
.......>>.....>>>...>>>.>>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohy Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		Y21 S25 F26 K27 Q34 R62 N64 R69 A71 K74 P84 A85 K86 Q96 A100 N101 H116 Q118 Q121 S141
Binding residue
(residue number reindexed from 1)		Y12 S16 F17 K18 Q25 R53 N55 R56 A58 K61 P71 A72 K73 Q83 A87 N88 H103 Q105 Q108 S113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ohy, PDBe:7ohy, PDBj:7ohy
PDBsum7ohy
PubMed34813592
UniProtP05740|RL17A_YEAST Large ribosomal subunit protein uL22A (Gene Name=RPL17A)

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