Structure of PDB 7of7 Chain P Binding Site BS01

Receptor Information
>7of7 Chain P (length=141) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VENEAVAPEFTNRNPRNLELLSVARKERGWRTVFPSREFWHRLRVIRTQH
HVEALVEHQNGKVVVSASTREWAIKKHLYSTRNVVACESIGRVLAQRCLE
AGINFMVYQPTPWEAASDSMKRLQSAMTEGGVVLREPQRIY
Ligand information
>7of7 Chain A (length=1376) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccaaaccuuagccaaacca
uuuacauaaaguauaggcgauagaaauugauggcgcaauagauauaguac
cgcaagggaaagaaagcauaauauagcaaggacuaaccccuauaccuucu
gcauaaugaauuaacuagaaauaacuuugcaaggagagccaaagcuaaga
cccccgaaaccagacgagcuaccuaagaacagcuaaaagagcacacccgu
cuauguagcaaaauagugggaagauuuauagguagaggcgacaaaccuac
cgagccuggugauagcugguuguccaagaugaaucuuaguucaacuuuaa
auuugcccacagaacccaaauccccuuguaaauuuaacuguuaguccaaa
gaggaacagcucuuuggacacuaggaaaaaaccuuguagagagaguaaaa
aauuuaacacccauaguaggccuaaaagcagccaccaauuaagaaagcgu
ucaagcucaacacaaaaaucccaaacauauaacugaacuccucacaccca
auuggaccaaucuaucacccuauagaagaacuaauguuaguauaaguaac
augaaaacauucuccuccgcauaagccugcgucagcugacaauuaacagc
ccaauaucuacaaucaaccaacaagucuuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccuuccuuaaauagggauggcuccacgaggguucagc
ugucucuuacuuuuaaccagugaaauugaccugcccgugaagaggcgggc
auaacacagcaagacgagaagacccuauggagcuuuaauuuauuaaugca
aacaccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaa
ccuccgagcaguacaugcuaagacuucaccagucaaagcgaaccuuugau
ccaauaacuugaccaacggaacaaguuacccuagggauaacagcgcaauc
cuauucuagaguccauaucaacaauaggguuuacgaccucgauguuggau
caggacaucccgauggugcagccgcuauuaaagguucguuuguucaacga
uuaaaguccuacgugaucugaguucagaccggaguaauccaggucgguuu
cuaucuacuuuaauuccucccuguacgaaaggacaagagaaauaaggccu
acuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauu
auacccacacacccaagaacaggguu
<<<.......<<<<..............................<.....
.>...........<<.....>>.........>>.>>.............<
<....>>.......>>>...........<<<.......>>>...<.<...
.....>.>.<<<<<<.........<<<.<<..<<....>>...>>.>>>.
..<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>...<<<<.
<<<<........>>>>>>>>....>>>.>>>>>...<<.......>>...
...>.>>>>......>.>>..<<<<<<...<<<<....>>>><<<.<<<<
<<<<<<.....<<.......>>.....>>>>>>>>>>..>>>.<<<<<<<
<<<......>>>>>>>>>>...<<<......>>>....<<<.<<<...<.
.............<....<<<.........>>>....>.......<<<..
....>>>..........................>...>>>>>>.......
.>>>>>>...<<<<<......>>>>>.........>>>>>>.......<<
..<<<....>>><<<<..<<<<........<<<<..>>>>......<<<.
..<<<<......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
<......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<.<<<<.....>>>>..>>>....>>.>>>>.....
>..>>.>>>>>>>>>>>>.>>...........<<<<<........>>>>>
.......<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<
......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<..........
.>>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.....
.<<<....>>>............>>>>..>>>>>>.......<<<...<<
<<<<<...<<.......>>...>>>>>>>....>>.>......<<<<<<.
<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>
.....>>>>>..>...>>>.>>>...<<<<<<<....>>>.>>>>....>
>..>>>.>>...<<<.<<<.................>>>.>>><<<<<..
.<<<....>>>.>>>>>......<<<.<............>.>>>.....
..........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of7 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R66 Y179
Binding residue
(residue number reindexed from 1)		R28 Y141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008097 5S rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0035928 rRNA import into mitochondrion
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of7, PDBe:7of7, PDBj:7of7
PDBsum7of7
PubMed34135319
UniProtQ9H0U6|RM18_HUMAN Large ribosomal subunit protein uL18m (Gene Name=MRPL18)

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