Structure of PDB 7ko4 Chain P Binding Site BS01

Receptor Information
>7ko4 Chain P (length=274) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL
QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADR
KYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQ
AEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL
YAQKLKYKAISEELDHALNDMTSI
Ligand information
>7ko4 Chain R (length=29) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MDAIKKKMQMLKLDKENALDRAEQAEADK
Receptor-Ligand Complex Structure
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PDB7ko4 The structure of the native cardiac thin filament at systolic Ca 2+ levels.
Resolution8.0 Å
Binding residue
(original residue number in PDB)		L278 M281 S283 I284
Binding residue
(residue number reindexed from 1)		L268 M271 S273 I274
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0051015 actin filament binding
Biological Process
GO:0007015 actin filament organization
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ko4, PDBe:7ko4, PDBj:7ko4
PDBsum7ko4
PubMed33753506
UniProtP42639|TPM1_PIG Tropomyosin alpha-1 chain (Gene Name=TPM1)

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