Structure of PDB 7ki0 Chain P Binding Site BS01

Receptor Information
>7ki0 Chain P (length=30) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HGEGTFTSDVSSYLEGQAAKEFIAWLVRGR
Ligand information
Ligand IDWF1
InChIInChI=1S/C12H24N2O7/c13-1-3-18-5-7-20-9-11(15)14-2-4-19-6-8-21-10-12(16)17/h1-10,13H2,(H,14,15)(H,16,17)
InChIKeyYQZVQKYXWPIKIX-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7C(COCCOCC(=O)NCCOCCOCC(=O)O)N
CACTVS 3.385NCCOCCOCC(=O)NCCOCCOCC(O)=O
ACDLabs 12.01C(OCCOCC(O)=O)CNC(COCCOCCN)=O
FormulaC12 H24 N2 O7
Name17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid
ChEMBL
DrugBank
ZINCZINC000104843043
PDB chain7ki0 Chain P Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ki0 Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q23 K26 E27
Binding residue
(residue number reindexed from 1)		Q17 K20 E21
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ki0, PDBe:7ki0, PDBj:7ki0
PDBsum7ki0
PubMed34260945
UniProtP01275|GLUC_HUMAN Pro-glucagon (Gene Name=GCG)

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