Structure of PDB 6wqn Chain P Binding Site BS01

Receptor Information
>6wqn Chain P (length=44) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
Ligand information
>6wqn Chain 1 (length=2687) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaa
ggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugau
ccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucg
auaugugaauacauagcauaucagaaggcacacccggagaacugaaacau
cuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggcg
agcgaaacgggaagagcccaaaccaacguugggguuguaggacacucuag
uuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaag
guaauaauccuguagucgaaaauguugucucucuugaguggauccugagu
acgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaa
ggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaag
gugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcu
uacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaau
gaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagcc
guagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccg
aaaccaggugaucuacccuuggucagguugaaguucagguaacacugaau
ggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggua
gcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauag
cuuuagggcuagccucaagugaugauuauuggagguagagcacuguuugg
acgagcgaauucagacaaacuccgaaugccaauuaauuuaacuugggagu
cagaacaugggugauaagguccguguucgaaagggaaacagcccagacca
ccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguaca
gagugacacugcgccgaaaauguaccggggcuaaacauauuaccgaagcu
guggauuguccuuuggacaaugguaggagagcguucuaagggcguugaag
caugaucguaaggacauguggagcgcuuagaagugagaaugccgguguga
guagcgaaagacgggugagaaucccguccaccgauugacuaagguuucca
gaggaaggcucguccgcucuggguuagucggguccuaagcugaggccgac
aggcguaggcgauggauaacagguugauauuccuguaccaccuauaaucg
uaucgauggggggacgcaguaggauaggcgaagcgugcgauuggauugca
cgucuaagcaguaaggcugcgguagcugagcugugauggggagaagaccu
ucgagucguugauuucacacugccgagaaaagccucuagauagaaaauag
gugcccguaccgcaaaccgacacagguagucaagaugagaauucuaaggu
gagcgagcgaacucucguuaaggaacucggcaaaaugaccccguaacuuc
gggagaaggggugcucuuuaggguuaacgcccagaagagccgcagugaau
aggcccaagcgacuguuuaucaaaaacacaggucucugcuaaaccguaag
gugauguauaggggcugacgccugcccagugcuggaagguuaagaggagu
gguuaggcgaagcuacgaaucgaagccccaguaaacggcggccguaacua
uaacgguccuaagguagcgaaauuccuugucggguaaguuccgacccgca
cgaaaggcguaacgauuugggcacugucucaacgagagacucggugaaau
cauaguaccugugaagaugcagguuacccgcgacaggacggaaagacccc
guggagcuuuacuguagccugauauugaaauucggcuuucuaacccgcac
cacuuaucguggugggagacagugucaggcgggcaguuugacuggggcgg
ucgccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguu
ggaaaucauucauagaguguaaaggcauaagggagcuugacugcgagacc
uacaagucgagcagggucgaaagacggacuuagugauccggugguuccgc
auggaagggccaucgcucaacggauaaaagcuaccccggggauaacaggc
uuaucucccccaagaguucacaucgacggggagguuuggcaccucgaugu
cggcucaucgcauccuggggcuguagucggucccaaggguugggcuguuc
gcccauuaaagcgguacgcgagcuggguucagaacgucgugagacaguuc
ggucccuauccgucgugggcguaggaaauuugagaggagcuguccuuagu
acgagaggaccgggauggacauaccucugguguaccaguugucgugccaa
cggcauagcuggguagcuauguguggacgggauaagugcugaaagcaucu
aagcaugaagccccccucaagaugagauuucccaacuucgguuauaagau
cccucaaagaugaugagguuaauagguucgagguggaagcauggugacau
guggagcugacgaauacuaaucgaucgaagacuuaau
.<<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<......
<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>.....>
>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<
<<<<<...........>>>>>>.>>.>>....<<<<<......<......
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..<<<....<<......>>.......<<<.......<
........<<<<<<<<<.<<<...<<<<<......>>>>>((......<<
<.....))>>>...>>>...>>>>>>>>.>.>..........>>>.....
.<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..
>>>......>>.>>>>>>>.>>...............<<....>>....>
>.........<<<<....>>>>..................>>>>>>>>>>
>.......<<<<..<<<<......>>>>..>>>>...<.<........>.
>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<
..<<<<<<<.....<<<<<<<<<..<<<....<<<<<........>>>>>
.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>.
..<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<
<<....>>>>><<<<<<<<<...<<<<<<<<<......<<...<<<<<<<
..........>>>>>>>..>>.......>>>>.>>>>>..>>>>>>>.>>
..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<<...
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>>>><<<<<<.....>>>>>>....>>>>>><.<<<<<<<.<.......<
<<<<.<<....>>.>>>>>....>.>>>>>>>..>.....>>>>>><...
...<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<
<<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<...
.>>>...>>>...>>...<<<<<........>>>>>))<<<<<<......
..<<...<<<<....<<<<...<<...<......<<<.........>>>.
..<.....<<<...<<.........>>...>>>......>..........
.........>....>>...>>>>.........>>>.>.>>.......>>>
>>>>>>>..>>.....<<......>>>>>>>.<<<<....>.>>>..>>>
>..<<<<....<<<<<<<<.<<.........<.....<<<<<........
.......>>>>><<<<<<<.<<<<....>>>>.>>>>>>>..........
..<<<<<<<<<..<<<.........>>>..<<<<<<<.....<<<....>
>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<
<<<........>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.....
..>>>>>>........<...........<<<<<<.....>>>>>>.....
>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>>>.>.....
>.....<<<<<........>>>>>..<<<<<<<<.<<<.<<......<<<
<.<<<<<<..<<<<<.<<<<<<<<<.<<<<......>>>>....<<.<<<
<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>
>><<<<<<...........>>>>>>..<<...<<<<<<<......<<<..
.....>>>........<<.[.(((>>....>>>>>>>...<<<<..<<<.
.....>>>..>>>>.<<<....>>>.>>)))]......<<<<<<.<<<..
>>>>..>>>>>>>>>.............>>>>..>>>>>>.......<<<
<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<
<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....
>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>
....>>..>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<....
...........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<......
>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<..........
.>>>>>...>>>>.>>>>.......>>>>>>>.<<<....>>>....<<<
<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>
>>...>>>..>>>>>.>>>...>>>>....>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wqn Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
V2 K3 R4 T5 Y6 Q7 P8 K10 K12 H13 H17 G18 F19 R20 R22 K26 N27 K30 R34 R35 R36 K38 G39 R40 K41
Binding residue
(residue number reindexed from 1)
V1 K2 R3 T4 Y5 Q6 P7 K9 K11 H12 H16 G17 F18 R19 R21 K25 N26 K29 R33 R34 R35 K37 G38 R39 K40
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6wqn, PDBe:6wqn, PDBj:6wqn
PDBsum6wqn
PubMed32566908
UniProtQ2FUQ0|RL34_STAA8 Large ribosomal subunit protein bL34 (Gene Name=rpmH)

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