Structure of PDB 6oj6 Chain P Binding Site BS01

Receptor Information
>6oj6 Chain P (length=1072) Species: 444185 (Simian rotavirus A strain RRV) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKYNLILSEYLSFIYNSQSAVQIPIYYSSNSELENRCIEFHSKCLENSKN
GLSLKKLFVEYSDVIENATLLSILSYSYDKYNAVERKLVKYAKGKPLEAD
LTVNELDYENNKITSELFPTAEEYTDLLMDPAILTSLSSNLNAVMFWLEK
HENDVAEKLKIYKRRLDLFTIVASTVNKYGVPRHNAKYRYEYEVMKDKPY
YLVTWANSSIEMLMSVFSHEDYLIARELIVLSYSNRSTLAKLVSSPMSIL
VALVDINGTFITNEELELEFSNKYVRAIVPDQTFDELKQMLDNMRKAGLT
DIPKMIQDWLVDCSIEKFPLMAKIYSWSFHVGFRKQKMLDAALDQLKTEY
TEDVDDEMYREYTMLIRDEVVKMLEEPVKHDDHLLQDSELAGLLSMSSAS
NGESRQLKFGRKTIFSTKKNMHVMDDMANGRYTPGIIPPVNVDKPIPLGR
RDVPGRRTRIIFILPYEYFIAQHAVVEKMLIYAKHTREYAEFYSQSNQLL
SYGDVTRFLSNNSMVLYTDVSQWDSSQHNTQPFRKGIIMGLDMLANMTND
ARVIQTLNLYKQTQINLMDSYVQIPDGNVIKKIQYGAVASGEKQTKAANS
IANLALIKTVLSRISNKYSFATKIIRVDGDDNYAVLQFNTEVTKQMVQDV
SNDVRETYARMNTKVKALVSTVGIEIAKRYIAGGKIFFRAGINLLNNEKK
GQSTQWDQAAVLYSNYIVNRLRGFETDREFILTKIMQMTSVAITGSLRLF
PSERVLTTNSTFKVFDSEDFIIEYGTTDDEVYIQRAFMSLSSQKSGIADE
IAASSTFKNYVSRLSEQLLFSKNNIVSRGIALTEKAKLNSYAPISLEKRR
AQISALLTMLQKPVTFKSSKITINDILRDIKPFFTVNEAHLPIQYQKFMP
TLPDNVQYIIQCIGSRTYQIEDDGSKSAISRLISKYSVYKPSIEELYKVI
SLHENEIQLYLISLGIPKIDADTYVGSKIYSQDKYRILESYVYNLLSINY
GCYQLFDFNSPDLEKLIRIPFKGKIPAVTFILHLYAKLEVINHAIKNGSW
ISLFCNYPKSEMIKLWKKMWNI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6oj6 In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
Resolution4.2 Å
Binding residue
(original residue number in PDB)
S398 A400 S401 N402 T414 T418 R452 I462 Q496 S497 S591 E593 K594 K597 K700 K701 L997 N1000
Binding residue
(residue number reindexed from 1)
S397 A399 S400 N401 T413 T417 R451 I461 Q495 S496 S590 E592 K593 K596 K699 K700 L996 N999
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
Cellular Component
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6oj6, PDBe:6oj6, PDBj:6oj6
PDBsum6oj6
PubMed31233764
UniProtB3F2X2

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