Structure of PDB 6nud Chain P Binding Site BS01

Receptor Information
>6nud Chain P (length=212) Species: 1308 (Streptococcus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFAKIKFSAQIRLETGLHIGGSDAFAAIGAIASPVIKDPITNIPIIPGSS
LKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDA
FLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFEL
IYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFEKLKAT
TVFGNYDVKTLN
Ligand information
>6nud Chain H (length=40) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acggaaacuuucguaacuguuuaauucuguucacuuauuc
........................................
Receptor-Ligand Complex Structure
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PDB6nud Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
G21 K53 G54 K55 R57 S73 G84 S86 K92 F122 E123 N124 T125 I126 R136 G183 G184 S185
Binding residue
(residue number reindexed from 1)
G20 K52 G53 K54 R56 S72 G83 S85 K91 F121 E122 N123 T124 I125 R135 G182 G183 S184
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:6nud, PDBe:6nud, PDBj:6nud
PDBsum6nud
PubMed30814678
UniProtA0A0A7HIF0|CSM3_STRTR CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

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