Structure of PDB 6hma Chain P Binding Site BS01

Receptor Information
>6hma Chain P (length=102) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGA
PTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKI
NA
Ligand information
>6hma Chain A (length=2834) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgauga
aggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuuga
uccagagauuuccgaauggggaaacccagcaugaguuaugucauguuauc
gauaugugaauacauagcauaucagaaggcacacccggagaacugaaaca
ucuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggc
gagcgaaacgggaagagcccaaaccaacaagcuugcuuguugggguugua
ggacacucuacggaguuacaaaggacgacauuagacgaaucaucuggaaa
gaugaaucaaagaagguaauaauccuguagucgaaaauguugucucucuu
gaguggauccugaguacgacggagcacgugaaauuccgucggaaucuggg
aggaccaucuccuaaggcuaaauacucucuagugaccgauagugaaccag
uaccgugagggaaaggugaaaagcaccccggaaggggagugaaauagaac
cugaaaccgugugcuuacaaguagucagagcccguuaaugggugauggcg
ugccuuuuguagaaugaaccggcgaguuacgauuugaugcaagguuaagc
aguaaauguggagccguagcgaaagcgagucugaauagggcguuuaguau
uuggucguagacccgaaaccaggugaucuacccuuggucagguugaaguu
caggcugaauggaggaccgaaccgacuuacguugaaaagugagcggauga
acugaggguagcggagaaauuccaaucgaaccuggagauagcugguucuc
uccgaaauagcuuuagggcuagccucaagugaugauuauuggagguagag
cacuguuuggacgaggggccgguuaccgaauucagacaaacuccgaaugc
caauuaauuuaacuugggagucagaacaugggugauaagguccguguucg
aaagggaaacagcccagaccaccagcuaaggucccaaaauauauguuaag
uggaaaaggauguggcguugcccagacaacgucgagugacacugcgccga
aaauguaccggggcuaaacauauuaccgaagcuguggauuguccuuugga
caaugguaggagagcguucuaagggcguugaagcaugaucguaaggacau
guggagcgcuuagaagugagaaugccggugugaguagcgaaagacgggug
agaaucccguccaccgauugacuaagguuuccagaggaaggcucguccgc
ucuggguuagucggguccuaagcugaggccgacaggcguaggcgauggau
aacagguugauauuccuguaccaccuauaaucguuuuaaucgaugggggg
acgcaguaggauaggcgaagcgugcgauuggauugcacgucuaagcagua
aggcugaguauugguacucguuaaggcugagcugugauggggagaagaca
uugugucuucgagucguugauuucacacugccgagaaaagccucuagaua
gaaaauaggugcccguaccgcaaaccgacacagguagucaagaugagaau
ucuaaggugagcgagcgaacucucguuaaggaacucggcaaaaugacccc
guaacuucgggagaaggggugcucuuuaggguuaacgcccagaagagccg
cagugaauaggcccaagcgacuguuuaucaaaaacacaggucucugcuaa
accguaaggugauguauaggggcugacgccugcccggugcuggaagguua
agaggagugguuagcuucugcgaagcuacgaaucgaagccccaguaaacg
gcggccguauaacgguccuaagguagcgaaauuccuugucggguaaguuc
cgacccgcacgaaaggcguaacgauuugggcacugucucaacgagagacu
cggugaaaucauaguaccugugaagaugcagguuacccgcgacaggacgg
aaagaccccguggagcuuuacuguagccugauauugaaauucggcacgcu
uguacaggauagguaggagccuuugaaacgugagcgcuagcuuacgugga
ggcgcuggugggauacuacccagcuguguuggcuuucuaacccgcaccac
uuaucguggugggagacagugucaggcgggcaguuugacuggggcggucg
ccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguugga
aaucauucauagaguguaaaggcauaagggagcuugacugcgagaccuac
aagucgagcagggucgaaagacggacuuagugauccggugguuccgcaug
gaagggccaucgcucaacggauaaaagcuaccccggggauaacaggcuua
ucucccccaagaguucacaucgacggggagguuuggcaccucgaugucgg
cucaucgcauccuggggcuguagucggucccaaggguugggcuguucgcc
cauuaaagcgguacgcgagcuggguucagaacgucgugagacaguucggu
cccuauccgucgugggcguaggaaauuugagaggagcuguccuuaguacg
agaggaccgggauggacauaccucugguguaccaguugucgugccaacgg
cauagcuggguagcuauguguggacgggauaagugcugaaagcaucuaag
caugaagccccccucaagaugagauuucccaacuucgguuauaagauccc
ucaaagaugaugagguuaauagguucgagguggaagcauggugacaugug
gagcugacgaauacuaaucgaucgaagacuuaau
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>.>>.>>....<<<<<......<<....
>>.......>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<<..>>>>>>>>>......<
<<<<<<<<...<<<<.......<<<<<<<<<<.<<<...<<<<<......
>>>>>((......<<<.....))>>>...>>>...>>>>>>>>>>>>>>.
>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<<<
<<..<<<<>>>>>..)))......]].>>>>>>>.]].............
..<<....>>....]].........<<<<....>>>>.............
}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>>.
..<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<...<<
<.....>>>...>>>...<<....>>..<<<<.....>>>>.....>>>>
>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<
<<<.>>>>>>.....>>>...<<<.<<<<<........>>>>>>>>....
>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>..<<<
<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<
...<<<<<<<<...<<.........>>...>>>>>>>>..>>.>.....>
>>>>.>>>>..>>>>>>>.>>..<<<<<<<<<<......>>>>>>>>>>.
...<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<....
.......<<..<<<<.<<<<........<..>....>>>>.>>>>.>>..
.........))).....>>>>>>.>>>...>>>>>>><<<<<<<...>>>
>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>
>>...>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<..
.....>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>
>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>..
.<<<<<........>>>>>))<<<<<<<..........<<<...<<<<..
..<<<<...<<...<....<.<<<.....{...>>>.>.<....<<<<..
.<<<.<<<<<<..>>>>>>......>>>...>>>>.....>.........
.................>....>>...>>>>.........>>>>..>>>.
....>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<.......
>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<<<<<<.<..........>.>>>>>>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<.....
<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<<<..
.<<...<<<<<<...........>>>>>>...>>...>>>>>>>>..>>>
>><<<<<.....>>>>>........<...........<<<<<<.....>>
>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>>>>>>>.>>
>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.(((.[[
......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<.<<<<<<<<<.
..............<<..<<.........<<<<<<....>>>>>>.....
.>>............>>.....>.>>>>>>>>.>>>>....<<.<<<<<<
.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<....
..>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>
>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.<
.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<
<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>
>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>...
.]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.......
........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.}..>>>>
>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>
>>>....>>>.>>>>.......>>>>>>>.<<<....>>>....<<<<<<
<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>.
..>>>..>>>>>.>>>...>>>>....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6hma Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus
Resolution2.65 Å
Binding residue
(original residue number in PDB)
G9 K10 F21 E23 R67 K69 K70 Y76 R78 R79 K80 K83 R84 K85 K86 H88 Q90 Y92
Binding residue
(residue number reindexed from 1)
G9 K10 F21 E23 R67 K69 K70 Y76 R78 R79 K80 K83 R84 K85 K86 H88 Q90 Y92
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6hma, PDBe:6hma, PDBj:6hma
PDBsum6hma
PubMed
UniProtQ2FXS8|RL21_STAA8 Large ribosomal subunit protein bL21 (Gene Name=rplU)

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