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Receptor Information

>5zza Chain P (length=119) Species: 1841599 (Candidatus Odinarchaeum yellowstonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MSLEQLAGRLISGDIGATAVIKMTGEIIYQSPNWSVDGVHAINVYKNREP
SIIIQGVKYSVIDVNEDRLIATNVGGQGHIVGAVAGGKALLIGYVSPNGD
ARTAYIQIDKTARQLSKIL

Ligand ID

LAB

InChI

InChI=1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1

InChIKey

NSHPHXHGRHSMIK-JRIKCGFMSA-N

SMILES

Software	SMILES
ACDLabs 10.04	O=C3OC2CC(OC(O)(C1NC(=O)SC1)C2)CCC(C=CCCC(=C3)C)C
CACTVS 3.341	C[C@H]\1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(C)/CC\C=C\1
OpenEye OEToolkits 1.5.0	C[C@H]\1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)\C=C(/CC\C=C1)\C
OpenEye OEToolkits 1.5.0	CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C
CACTVS 3.341	C[CH]1CC[CH]2C[CH](C[C](O)(O2)[CH]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1

Formula

C20 H29 N O5 S

Name

LATRUNCULIN B

PDB chain

5zza Chain P Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5zza Genomes of Asgard archaea encode profilins that regulate actin.
Resolution	1.53 Å
Binding residue (original residue number in PDB)	D100 R102
Binding residue (residue number reindexed from 1)	D100 R102
Annotation score	1

Enzyme Commision number

	Molecular Function
GO:0003779	actin binding

	Cellular Component
GO:0005737	cytoplasm
GO:0005856	cytoskeleton

PDB	RCSB:5zza, PDBe:5zza, PDBj:5zza
PDBsum	5zza
PubMed	30283132
UniProt	A0A1Q9N7W7\|PROF_ODILC Odin profilin (Gene Name=OdinLCB4_14170)

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Structure of PDB 5zza Chain P Binding Site BS01