Structure of PDB 5zlu Chain P Binding Site BS01

Receptor Information
>5zlu Chain P (length=119) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYA
AQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVD
DTPVPHNGCRPKKKFRKAS
Ligand information
>5zlu Chain G (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggug
aauacguucccgggccuuguacacaccgcccgucacgccaugggagcggg
cucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcc
cgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcu
ggaucaccuccuuu
....(((.....<<<<..))).<<<<.<<<<<...<<<<<<.........
.<<<...<<..<<..<<<<<<<<.......>>>>>>>>..>>>>......
.<<.......<<<<<<<...<<...<<<<<<<.<<<<<....<<<<<...
...>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<
<<<...>>>>.>>>>>>>..>>.>>>>>>><<<....<<....<<<<<<<
.......>>>>>>>..>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>...
......<<.<<<....<<<<....>>>>..>>>>>.>.>>>>>...<<<<
......<<<<<..>>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<((....<<<<<......
...)).........>>>>>>>>>>..>>>>>>>>>..........<<.(.
.....<<<<...<<<..<<<<<.<<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>....<<<<<<.<...<<<<<<
<....<...<<<....<<<......>>>.......>>>....>.......
...<<....>>.>>>>>>>..>.>>>.>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<..<<<<<<<<.......>>>>>>>>...<<...)>>.....>>>>
>>..>>..<<......<<<<....>>>>....>>...>>>>...<<<..<
<<<<<<.<<..<<<<<..<<<<<<<<<<......<<........>>....
......<<<<<<<......<.<...<<..<<<<<........>>>>>...
<<......>>...>>...>.>.<<<.<<<..<<<<<<.......<<<<<.
<<<....>>>..<<<<......>>>>...>>>>>.....<<<<.<<<..<
...<<...<<<.....>>>.>>....>..>>>.....<<<<<....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>.............<<<<<........>>
>>>............>>>>>.....<<<<<<<..........>>>>>>>.
.....>>...>>>>>>>.>>.>.....<..<<.<.<<<..<<<..<<<<<
<<<<<<<<.....<<<<....<<<....>>>.>>>>....>>>>>>>>>>
>>>..>>>..>>>..>.>>...>.....<<<<.<<<<....>>>>.>>>>
..............
Receptor-Ligand Complex Structure
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PDB5zlu Ribosome protection by antibiotic resistance ATP-binding cassette protein.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y20 H22 N26 N27 I29 T31 N38 W42 G46 G52 K55 R85 P113 P115 H116 N117 C119 R120 K123
Binding residue
(residue number reindexed from 1)		Y10 H12 N16 N17 I19 T21 N28 W32 G36 G42 K45 R75 P103 P105 H106 N107 C109 R110 K113
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zlu, PDBe:5zlu, PDBj:5zlu
PDBsum5zlu
PubMed29712846
UniProtP80376|RS11_THET8 Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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