Structure of PDB 5mq0 Chain P Binding Site BS01

Receptor Information
>5mq0 Chain P (length=69) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKFSWRKGTAFGRY
INDMTKSEYHQEFLHKHVR
Ligand information
>5mq0 Chain 2 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acgaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuuug
uaacaacugaaaugaccuaggcucauuguuacggacgggaagaggagacg
ucgcgacccucgcagucguucuugacuggucgcuugauguuucuucuucc
cguuc
.................................................<
<<<<<<......<<<<<<>>>.>>>>>>>>>><<<<<<<<<<<.<<<<<<
<<<<<<.<<.....<<<<....>>>>.>>>>>>..>>>>>>>>.>>>>>>
>>>>>
Receptor-Ligand Complex Structure
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PDB5mq0 Structure of a spliceosome remodelled for exon ligation.
Resolution4.17 Å
Binding residue
(original residue number in PDB)
H5 R6 P7
Binding residue
(residue number reindexed from 1)
H2 R3 P4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0071013 catalytic step 2 spliceosome

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Cellular Component
External links
PDB RCSB:5mq0, PDBe:5mq0, PDBj:5mq0
PDBsum5mq0
PubMed28076345
UniProtQ03772|CWC15_YEAST Pre-mRNA-splicing factor CWC15 (Gene Name=CWC15)

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