Structure of PDB 5mam Chain P Binding Site BS01

Receptor Information
>5mam Chain P (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>5mam Chain I (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB5mam Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
Resolution2.2 Å
Binding residue
(original residue number in PDB)
F1 V2 H5
Binding residue
(residue number reindexed from 1)
F1 V2 H5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:5mam, PDBe:5mam, PDBj:5mam
PDBsum5mam
PubMed28348075
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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