Structure of PDB 5lj3 Chain P Binding Site BS01

Receptor Information
>5lj3 Chain P (length=36) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKF
Ligand information
>5lj3 Chain U (length=141) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagcuuuacagaucaauggcggagggaggucaacaucaagaacugugggc
gccuauagaacuuauaacgaacaugguucuugccuuuuaccagaaccauc
cggguguugucuccauagaaacagguaaagcuguauuuuuu
<<<<<<<<<.......<.......<<<<<.<<<<<<<.....<<<<<<<.
.>>>>>>>..............<<<<<<<<...........>>>>>>>>.
..>>>>>>>>>>>>......>...>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB5lj3 Cryo-EM structure of the spliceosome immediately after branching.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		R29 P32 G33 H34 T35
Binding residue
(residue number reindexed from 1)		R23 P26 G27 H28 T29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0071013 catalytic step 2 spliceosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5lj3, PDBe:5lj3, PDBj:5lj3
PDBsum5lj3
PubMed27459055
UniProtQ03772|CWC15_YEAST Pre-mRNA-splicing factor CWC15 (Gene Name=CWC15)

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