Structure of PDB 5cd4 Chain P Binding Site BS01

Receptor Information
>5cd4 Chain P (length=359) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRK
SGYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSV
DEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAI
RVNLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWF
TAVDDLQSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATH
VVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDG
FLQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQL
KSWVRNNGE
Ligand information
>5cd4 Chain X (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaaaccgacgguauuguucagauccuggcuugccaacaggaguuccccg
cgccagcgggg
.............................................<<<<<
<....>>>>>>
Receptor-Ligand Complex Structure
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PDB5cd4 Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N19 R20 K27 S40 Q42 S43 K45 R46 M166 F200 T201 V203 A212 A265 K266 R268
Binding residue
(residue number reindexed from 1)		N19 R20 K27 S40 Q42 S43 K45 R46 M166 F200 T201 V203 A209 A262 K263 R265
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5cd4, PDBe:5cd4, PDBj:5cd4
PDBsum5cd4
PubMed26243775
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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