Structure of PDB 3hda Chain P Binding Site BS01

Receptor Information
>3hda Chain P (length=382) Species: 556 (Dickeya chrysanthemi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVSWNGTNVFGKSANLTFKFLQSVSSIPSGDTGFVKFNAEQIEQAKLSLQ
SWSDVANLTFTEVTGNKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQG
AGSSWYNYNQSNIRNPGSEEYGRQTFTHEIGHALGLAHPGYNGHYGGAPM
IDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWD
AGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGS
GNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDST
VAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAAN
SITNLWLHEAGHSSVDFLVRIVGQAAQSDIIV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3hda Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
Resolution2.131 Å
Binding residue
(original residue number in PDB)		A150 Y151 A152 Y154 Y181 H188 H192
Binding residue
(residue number reindexed from 1)		A90 Y91 A92 Y94 Y121 H128 H132
Enzymatic activity
Enzyme Commision number 3.4.24.40: serralysin.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0031012 extracellular matrix

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3hda, PDBe:3hda, PDBj:3hda
PDBsum3hda
PubMed19558324
UniProtP16317|PRTC_DICCH Serralysin C (Gene Name=prtC)

[Back to BioLiP]