Structure of PDB 2wtt Chain P Binding Site BS01

Receptor Information
>2wtt Chain P (length=43) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQR
Ligand information
>2wtt Chain M (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DTYYLQVRGRENFEILMKLKESLELMELV
Receptor-Ligand Complex Structure
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PDB2wtt Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
L396 Q397
Binding residue
(residue number reindexed from 1)
L41 Q42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2wtt, PDBe:2wtt, PDBj:2wtt
PDBsum2wtt
PubMed19815500
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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