Structure of PDB 2i60 Chain P Binding Site BS01

Receptor Information
>2i60 Chain P (length=300) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVGAGS
CNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTV
QCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVIN
CTGAGHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTH
SFNCGGEFFYCNSTQLFTWRNITLPCRIKQIINMWQEVGKAMYAPPIRGQ
IRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
Ligand information
>2i60 Chain S (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGRCAPTFCACV
Receptor-Ligand Complex Structure
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PDB2i60 Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		G366 G367 D368 E370 I371 N425 M426 W427 E429 V430 G473 D474
Binding residue
(residue number reindexed from 1)		G192 G193 D194 E196 I197 N233 M234 W235 E237 V238 G281 D282
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:2i60, PDBe:2i60, PDBj:2i60
PDBsum2i60
PubMed18619974
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

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