Structure of PDB 1yyl Chain P Binding Site BS01

Receptor Information
>1yyl Chain P (length=301) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVGAGSC
NTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQ
CTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINC
TGAGHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHS
FNCGGEFFYCNSTQLFTWNDRNITLPCRIKQIINMWQEVGKAMYAPPIRG
QIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKI
E
Ligand information
>1yyl Chain S (length=27) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CNLHFCQLRCKSLGLLGKCAGSFCACV
Receptor-Ligand Complex Structure
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PDB1yyl Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
S1365 G1366 G1367 D1368 E1370 I1371 S1375 N1425 W1427 E1429 V1430 G1473 D1474
Binding residue
(residue number reindexed from 1)
S190 G191 G192 D193 E195 I196 S200 N234 W236 E238 V239 G282 D283
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yyl, PDBe:1yyl, PDBj:1yyl
PDBsum1yyl
PubMed15893666
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

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