Structure of PDB 1obf Chain P Binding Site BS01

Receptor Information

>1obf Chain P (length=335) Species: 85698 (Achromobacter xylosoxidans)

TIRVAINGYGRIGRNILRAHYEGGKSHDIEIVAINDLGDPKTNAHLTRYD
TAHGKFPGTVSVNGSYMVVNGDKIRVDANRNPAQLPWGALKVDVVLECTG
FFTTKEKAGAHIKGGAKKVIISAPGGADVDATVVYGVNHGTLKSTDTVIS
NASCTTNCLAPLVKPLNDKLGLQDGLMTTVHAYTNNQVLTDVYHEDLRRA
RSATMSMIPTKTGAAAAVGDVLPELDGKLNGYAIRVPTINVSIVDLSFVA
KRNTTVEEVNGILKAASEGELKGILDYNTEPLVSVDYNHDPASSTVDASL
TKVSGRLVKVSSWYDNEWGFSNRMLDTTVALMSAA

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 1obf Chain P Residue 341

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1obf The Structure of Glyceraldehyde 3-Phosphate Dehydrogenase from Alcaligenes Xylosoxidans at 1.7 A Resolution
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): T184 R199 R235
• Binding residue (residue number reindexed from 1): T184 R199 R235
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.2.1.-

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
• GO:0016491 oxidoreductase activity
• GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
• GO:0050661 NADP binding
• GO:0051287 NAD binding

Biological Process

• GO:0006006 glucose metabolic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:1obf, PDBe:1obf, PDBj:1obf
• PDBsum: 1obf
• PubMed: 12777799
• UniProt: P83696