Structure of PDB 7qep Chain O0 Binding Site BS01

Receptor Information

>7qep Chain O0 (length=90) Species: 284813 (Encephalitozoon cuniculi GB-M1)

NVTSSLLLAMRTGKYIVGFKRAIKSVIMKKAKCLVISSNFPSTKRKLLEY
YSVLAGGLPIIFHSANNEELGSITERGHRLGCISIIDQGE

Ligand information

>7qep Chain 1 (length=2319)

ucucuguucacgggauugauuggcauuagcggcgaugaaggacgugcagg
aggacgauaugcguuguuguugugacggugucugaauugugugcggugug
cacggggaccccuuggacuuaagcauaucaguaaagggaggagaagaaac
caaaugggauugccugaguagcggcgagugaaauggcaugagccugugug
guaacugcguggcggguuguguuuguggcagcagcggcgagugcgauuga
auucggaugcggagagggcgaugugccuguaggcgcggcggcuuuuuuug
ugaguaguguugcuugguagugcagcgcgaaugcggugguggaugcaccg
aaggcuaaauauggcugaugaccgauagcggauaaguagagugauugaag
ugugaaaaggaggaugaugagaaaugaaagugaauggagugaauggggga
uguucccgcccgucuugaaacacggaccaaggagacgacggcaggauugu
uuuccgagaggggaggaugcugcggucggacccgaaagauggugagcuau
guguguguugauugaagggaugcgaaaguguucuggaggaucuaagccgu
ucugacgugcaacucgauggcaugacaugugcauaggggcgaaagaccaa
acgaaccaucugguagcugguucccucugaaaugucucucaggacagcgg
cgacggguguaagauguuguaaagcacuaaugcgcugcguuaaacuuuga
agaugucuuuuaaguuguugccagugggcauacugugguaagcauggugu
gcgagaagggaugaaccuuuaagcgggcuaaggagucuuaugcaagguga
auccggcggccugauuuugacagccgaauugggcggcggagaaaauggaa
gggauugaauugcauuccgaugccugcgggggaguaucugaguaaggggg
cgguaucguucugcugaagguccugcgugagcggggguggaggggcgaua
ugugcagaucuugguagcaguaacaaggaaaugauuugcgcuggacgagg
guucccuguggcaggggugaaucgacuguggauacggaggugcauugaua
guuguguguauugcggcugggaggcgacuuggcugugacggaugggggcg
gcccuguccaggauagcagaacuggaugucugcugcggauuguuaugaug
cgaagcagcgaugggcgagccuguuccgaugaaaaagaggcugcuuuguc
guaccuagaccgcaucugguguccacuguuugccgcggaaguguuuugug
caagggccguaagggaagucggcaagauugauguguaacuucgggagaag
gauuggcucuagcgugcuagaacuguuuguuguggggaaucugacuguuu
acuaaaaacauagcuuuguguguggacgcaaagugaauucugcccagugc
acuuuuaguuacggccuguugggcuaagcgaguguaaacggcgggaguaa
cuaugacucucuuaagguagccaaaugccucgucauguaauuagugacgc
gcaugaauggagcaacgagauucccacugucccuacggccugucuuguga
accuacagccaagggaacgggcuugggcugaucagcggggaaagaagacc
cuguugagcuugacucuagcaugugugaagugcugggugcccagugcuuu
guggauggauguggggaguuuggcuggggcggcacgacugcuaaagacua
acgcagacguccuaaggcgggcucagcggggaaggaaaccacgcguggag
cacaagggcacaagccugcuugagacuguuccuauugcgggacuguuugg
gggaaacccuggccuagagaucccauguccuauugugcgugggacauggg
ugacagaaaaguuaccacagggauaacuggcuuguagcagccgagcgacc
auagcgacgcugcuuuuugauucuucgaugucggcucuuccuaucaucgc
gaagcagagauugcgaaguguuggauuguucacccaccaacagggaacgu
gagcuggguuuagaccgucgugagacagguuaguuuuacccuacugugug
gacugugcagcagaucuugauaguacgagaggaacucuugauugcgaccu
cugguggagcggcgugccugcuggcugcugcggagcuacgucgggaguau
aauggcugaaggccucuaagccugaagaccgacugcgcgguguguguggc
ggaagacgaccgcugugugugcaagcugugcggauggaggaggauuccga
cauuuugaggcugugcauu

[<<<<<<<<<<.......[..<<<<<<<<<..<......<<<<<<.....
...>>>.....<<<<<......>>>>>...>>>.....<<<<<<...>>>
>>>>....<<<<<<.....<......>......>>>>>.>.........<
<....>>...<<<<......<<.....>>.....>>>>...<<<......
....<<<<...>>>>...........<<<.<<.<<<.<.....<<<....
..>>>..((......<<<.....))>>>...>.>>>.>>.>>>.......
......<<<<<<<........>>>>>>>.....<<<<<..<.<<<>>>>>
..>>>........>>>>>>>.>>...............<<....>>....
]............................>>>>>>>>>>....<<<<...
....>>>>.<<<<........>>>><<<<<<....<<<<.<<<<.<<<..
...<<....>>....>>>.>>>>.>>>>..<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..
<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<
<<<<<....<<<<<<<<<...<<<...<<<<<<<.>>>>>>>..>.>>..
.>>>>>>>..>>...>>>>>>>.>>..<<<<<<<<<<.....>>>>>>>>
>>...<<<<......>>>>...<<<<<<...<<<.(....<<<<<.....
.<<<<...<<<<<<<............>>>>>>>..>>>>..........
.).......>>>>>.>>>...>>>>>>..<<<....>>>.....>>>>>>
<.<<<<<<<<<<......<.<<<<<<....>>>>>>.>...>>>>>>>>>
>..>.....>>>>>><<.....<<<<.<<<....>>><<<.<<<<<<.<<
...<<<<<<.>>>>>>....((<<<<<<......>>....<<<<......
..>>>>.))...<<<<<...<<<....>>>.........<<<<<<<....
<<<<<<<<<<<...((((...>>>>>>><.<<<<<<...<<.....>>..
....>>>>>>>.>>>>...>>>>>>>.............>>>>>...>>>
>..>>....<<......>>>>>>>><<<<.....>>>>...>>>......
...<<<<<<<<.<<.........<.....<<<.<....<<..>>.....>
.>>><<.<<<<<<..>>>>>>.>>..........<<<<<<<<<..<<<..
.......>>>..<<<<<<<........>>>>>>>...<<..<<<..<<<<
<<<<...<<<..<<<<<...>>>>>.>>>>>>>>>..>>>>><<<<<<..
.....>>>>>>........<...........<<<<<.......>>>>>..
...>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>...>>>>..
..>>....<<<<<........>>>>>....].<<<..<<<.<<......<
<<<.<<<<<<..<<<<<.<<<<.<<..<<<<<<<<<<..>>>>>>>>>>.
.....>>.>>>>..>>>>>...<<<.....>>>..<.<<<<.........
..>>>>.>..<<...<<<<<<<...<<<.<<.......>>.>>>.....<
<...(((>>....>>>>>>>...<<<.<<<<<......>>>>>.>>>..<
<<....>>>.>>))).......<<<<<<<<<..>>>.>..>>>>>>>>>.
.........>>>>..>>>>>>.......<<.<.<.<<<<<<...<<....
...>>...>>>>>>...>>..>>.......<<<<<.<<<<<<..<<<<<<
<<........>>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>....
.<<<<<<<<<..<<<<..<<...............>>..>>>>.<<<<..
..<<<...<<<<<<.<<.)))).>>>>>>>>...>>>..>>>>...<<.<
...<<<<...........>>>>....>>>...>>>>>>>>>......<<<
<<.......>>>>>....<<<<<<<<<.....<<<<..<<<....>>>..
>>>>....>>>>.>>>>>.

Receptor-Ligand Complex Structure

Structure summary

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Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

StatusManager callback set for APPLETREADYCallback f=Jmol._readyCallback cb=APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

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Jmol getValue ERRORCallback null

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• PDB: 7qep Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): G27 F28 K29 R30 P50 K53 H87 R88 G90
• Binding residue (residue number reindexed from 1): G18 F19 K20 R21 P41 K44 H78 R79 G81

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome

Cellular Component

• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit

External links

• PDB: RCSB:7qep, PDBe:7qep, PDBj:7qep
• PDBsum: 7qep
• UniProt: Q8SRU1

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