Structure of PDB 8vfz Chain O Binding Site BS01

Receptor Information
>8vfz Chain O (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNS
IRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK
CE
Ligand information
>8vfz Chain I (length=171) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttgtgtctcctgctctgtcagcagggcactgtacttgctgataccaggga
atgtttgttcttaaataccatcattccggacgtgtttgccttggccagtt
ttccatgtacatgcagaaagaagtttggactgatcaatacagtcctctgc
ctttaaagcaataggaaagat
Receptor-Ligand Complex Structure
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PDB8vfz Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 1)
Resolution4.1 Å
Binding residue
(original residue number in PDB)
K170 S174 Y175 I176 R213 S217 H220 L260 R261 R262 K264 R265
Binding residue
(residue number reindexed from 1)
K3 S7 Y8 I9 R46 S50 H53 L93 R94 R95 K97 R98
External links
PDB RCSB:8vfz, PDBe:8vfz, PDBj:8vfz
PDBsum8vfz
PubMed39121853
UniProtP55317|FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha (Gene Name=FOXA1)

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