Structure of PDB 8uu9 Chain O Binding Site BS01

Receptor Information
>8uu9 Chain O (length=134) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLVPKRVKYRREFRGNMRGRAKGGTEVAFGEYGLQAVEASWITNRQIEAA
RIAMTRYMKRGGKVWIKIFPHKSYTSKPIGVRMGKGKGAPEGWVSPVKRG
KIMFEIAGVPEDVAREALRLAAHKLPVKTKIVKR
Ligand information
>8uu9 Chain A (length=2899) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaaga
aggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguuga
uccagagauuuccgaaugggggaacccacuaucuuuagucggauaguauc
cuuacgugaauacauagcgugaggaaggcagacccagggaacugaaacau
cuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggcg
agcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguuguag
gacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugga
aaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccuc
cagaguggauccugaguacgacggaacacgugaaauuccgucggaauccg
ggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaacc
aguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacagu
uccugaaaccgugugccuacaaguaguuagagcccguuaaugggugauag
cgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguuaa
gcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaag
uaacaggucguagacccgaaaccaggugaucuacccauguccaggaugaa
gguaagguaauacuuacuggagguccgaacccacgcacguugaaaagugc
ggggaugagguguggguagcggagaaauuccaaucgaacuuggagauagc
ugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucaug
gagguagagcacuguuuggacuaggggaccgaauucagauaaacuccgaa
ugccauguacuuauacucgggagucagacugcgagugauaagauccguag
ucgaaagggaaacagcccagaccaccaguuaagguccccaaauauauguu
aaguggaaaaggaugugggguugcuuagacaaccaggauguuggcuuaga
agcagccaccauugaaagagugcguaauagcucacuggucgagugacccc
gcgccgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaac
cuagguucgugguaggagagcguucuaagggcggugaagucagaccggaa
ggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaaga
agggugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcuc
guccgcucaggguuagucgggaccuaagccgaggccgauaggcguaggcg
auggacaacagguagagauuccuguaccagugcuaauuguuuaaccgaug
gggugacacagaaggauagggaaucgcacgaauggaaaugugcguccaag
cagugagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugu
gauggggaagacggaaguuccugauuucacgcugucaagaaaagccucua
ggaagaguaguacugcccguaccgcaaaccgacacagguagaugaggaga
gaauccuaaggugagcgagagaacucucguuaaggaacucggcaaaauga
ccccguaacuucgggagaaggggugcucuauuagggugcaagcccgagag
agccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggucucu
gcaaaaccguaaggugacguauaggggcugacgccugcccggugcuggaa
gguuaagaggagugcuuagcuucggcgaagguacgaauugaagccccagu
aaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucg
gguaaguuccgacccgcacgaaaggcgcaacgaucugggcacugucucaa
cgagagacucggugaaauuauaguaccugugaagaugcagguuacccgcg
acaggacggaaagaccccguggagcuuuacugcaaccugauauggaaugu
uuguaccgcuuguacaggauagguaggagccgaagagacgugugcgcuag
cauacgaggaggcaauggugggauacuacccuggcuguaugaccauucua
acccgccacgcuaagcgcguggggagacagugucaggugggcaguuugac
uggggcggucgccuccuaaagaguaacggaggcgcccaaagguucccuca
gaauggauggaaaucauucgcagaguguaaaggcacaagggagcuugacu
gcgagacugacaagucgagcagggacgaaagucgggcuuagugauccggu
gguuccgcauggaagggccaucgcucaacggauaaaagcuaccccgggga
uaacaggcuuaucucccccaagaguccacaucgacggggagguuuggcac
cucgaugucggcucgucgcauccuggggcuguagucggucccaaggguug
ggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucguga
gacaguucggucccuauccgucgcgggcgcaggaaauuugagaggagcug
uccuuaguacgagaggaccgggauggacacaccgcugguguaccaguugu
uccgccaggagcaucgcuggguagcuauguguggcagggauaaacgcuga
aagcaucuaagcgugaagccccccucaagaugagauuucccauuucuucg
gaaaguaagaucccugaaagaugaucagguagauagguuuggaguggaag
uguagcgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....>
>......>>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<<
<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<....
..>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>>
>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......<
<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]...........
....<<....>>....]].........<<<<....>>>>...........
..}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>>
>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...
<<.......>>...>>>...<<....>>..<<<<.....>>>>......>
>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....
<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>>
>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>
.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<<
<.....<<<...<<<<<<<<...<<...>>...>>>>>>>>..>>.>...
..>>>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>
>>....<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.
..........<<..<<<<<<<<<<.......<<<<<.<<...<<<<....
...>>>>...>>.........<<......>>...>>>>>...>>>>>>>>
>>.>>...........))).....>>>>>>.>>>...>>>>>>><<<<<<
<..>>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....
>>.>>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<
<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<...
..>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>.
..>>...<<<<<........>>>>>))<<<<<<<<.<<......<<...<
<<<<...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<
<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>
...>>............>>>>>...>>>...>>>>........>>>>>..
>>..>>.>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<..
...>>>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<
<<<<....<<..>>.....>>>>><<<<<....<<<<....>>>>...>>
>>>............<<<<<<<<<..<<<.........>>>..<<<<<<<
.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..
<<<<..<<...<<<<<<.<<<..>>>..>>>>>>...>>..>>>>>>>>>
..>>>>><<<<<<.......>>>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.
<<<<<<.<<<.<.........<<<<<..<<<.......<<<<<<<....>
>>>>>>....>>>............>>>>>>.>>>.>>>>>>.>>>>>..
..<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<
<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...
<<<<<.<......>>>>>>.....<<.[.(((>>....>>>>>>>...<<
<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<
<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>..
.....<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>
.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<
<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....
>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<
<<<<...............>>>>>>>.<<<<<...<<<<...<<<<<<<<
<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<..
.........>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<..>
>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<
<<<<....>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uu9 Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
P4 R6 Y9 R11 F13 R14 G15 N16 R18 K22 Q46 K63 W65 F69 H71 K77 G80 R82 M83 G84 K85 G86 K87 H123 K124 P126
Binding residue
(residue number reindexed from 1)
P4 R6 Y9 R11 F13 R14 G15 N16 R18 K22 Q46 K63 W65 F69 H71 K77 G80 R82 M83 G84 K85 G86 K87 H123 K124 P126
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uu9, PDBe:8uu9, PDBj:8uu9
PDBsum8uu9
PubMed38407413
UniProtA0A0U4VSU8

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