Structure of PDB 8tj5 Chain O Binding Site BS01

Receptor Information
>8tj5 Chain O (length=1659) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKWSAIPFQTLYRSIESGEFDFDLFKEVLPDLQNLNLNTDKLKNNASRSQ
LEKGEIELSDGSTFKVNQEFIFEAISLSDELNLDEIVACELILSGDTTAN
NGKVQYFLRRQYILQIVSFIVNCFHEDTELYQELIKNGALVSNILSAFKF
IHTQLSEIKQQINKAQILENYNALFQQNIKFRRDFLLREYDILSQILYGL
VDKGAIMKNKDFILSLLHHVSELDSNDFFIIYYTPAFFHLFASLRVLPDA
DVKLLHSQFMKDLKDDSIYTKPVKVALIFIFFAYFIGWCKEDPKRRADTM
DFKTDVDEPMTSAVELGAIEQILIFAADTSIVEQDKSMELFYDIRSLLER
HIPRLIPKQLLDDEKIFSQTTNSTYNPASATDNMSGNNVNEYSYTTIVLS
DQTQEFFLSSFDDVLQTIITDCAFLLTKIKDAEEDSLLSGEDLTLDDISL
KADLERFFLSIYFFYASRPEYSCTFWSDKESNAYGFIEWCSRCNDNLMRS
CFYLMVSSLSFGPENALNVYHYFGENSSISWKNIAQCLSDYTKKISNFNS
SLHKRQQFSESTHNDIDSTAVALEEGLNEEAVIFLSSLLTLVGSVTYQVD
EDVKSSLSKVFSDVLFEFTKINTPLVGAAFKVISNLVPKLESSRTKFWSF
LDSLIFKDSSLNYSSESYRNAFTNVLTKYSDVLGFLQLFHNLISIHSREN
NSEYMVFGKLAFPTRLGQGYRKVGIWPYFDYIFNDILAHVDQIVDIRNKR
AVQLPILKIIYTGLCSFDYSVILNSIPAAANLDALVDCENFFNYVQECPA
IPIFNYIFTEKIYKSIFNVVDVGVDQLSIELEGGKNQAELLQLAVKIINK
VLDYQETYVEELFPIVKKHGKTDYFLPKNYSLHGLRSFYDAIFFNIPLVA
HLGLYVGVDDQILATNSLRILAKLSERSNGSVASLSKRNKLLTIFDSVDE
SARIKDAFITQLESSITDAGVLALKLELLDFLTSNLSNYSRTMTISHLLL
GFQVSNVISLGPNLATFISSGTSLLDSLISVLEASLNSITKDNIDYAPMR
LATAALEIILKLCRNPLTSGLLYSYLIKENFFERIMILDPQVTRFTTWNG
SPFDNSTEEKCKNFIESESVGAFLSFLAYRNYWTQYLGLFIHKISFSGTK
SEVLTYVNYLISNTMYSVRLFSFLDPLNYGNICEPKETLSIFTNVPLNLE
QVTLNKYCSGNIYDFHKMENLMRLIKRVRAESLHSNSFSLTVSKEQFLKD
ADVECIKAKSHFTNIISRNKALELNLSVLHSWVQLVQIIVTDGKLEPSTR
SNFILEVFGTIIPKISDYIEFNITFSEELVSLAVFLFDIYNRDRKLITDK
GTVDGRLYQLFKTCIQGINSPLSSVALRSDFYILANHYLSRVLSDQVGSE
KVLQDLRLGSKKLVEIIWNDVVYGEGTSRVTGILLLDSLIQLANRSKENF
ILDSLMKTTRLLLIIRSLKNTDALLNSTTEHINIDDLLYELTAFKATVFF
LIRVAETRGGASALIENNLFRIIAELSFLKVDPDLGLDLMFDEVYVQNSK
FLKVNVTLDNPLLVDKDANGVSLFELIVPIFQLISAVLVSMGSSNKAVVQ
TVKGLLNTYKRLVIGIFKRDLLREKEDKKNSSDPNNQSLNEMVKLIVMLC
TLTGYQNND
Ligand information
>8tj5 Chain h (length=17) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8tj5 Implications of a multiscale structure of the yeast nuclear pore complex.
Resolution6.6 Å
Binding residue
(original residue number in PDB)		I800 A804 N805 E884 E885
Binding residue
(residue number reindexed from 1)		I776 A780 N781 E860 E861
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0017056 structural constituent of nuclear pore
Biological Process
GO:0006913 nucleocytoplasmic transport
GO:0006999 nuclear pore organization
GO:0015031 protein transport
GO:0046822 regulation of nucleocytoplasmic transport
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0044611 nuclear pore inner ring

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8tj5, PDBe:8tj5, PDBj:8tj5
PDBsum8tj5
PubMed37738963
UniProtP47054|NU192_YEAST Nucleoporin NUP192 (Gene Name=NUP192)

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