Structure of PDB 8pj4 Chain O Binding Site BS01

Receptor Information
>8pj4 Chain O (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLA
DLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIE
AHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIM
TREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDVFVRKVKMLKKPK
FELGKLMELHG
Ligand information
>8pj4 Chain A (length=1754) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucugaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccuacuuggauaacugug
guaauucuagagcuaauacaugccgacgggcgcugacccccuucgcgggg
gggaugcgugcauuuaucaguggugacucuagauaaccucgggccgaucg
cacgccccccguggcggcgacgacccauucgaacgucugcccuaucaacu
uucgaugguagucgccgugccuaccauggugaccacgggugacggggaau
caggguucgauuccggagagggagccugagaaacggcuaccacauccaag
gaaggcagcaggcgcgcaaauuacccacucccgacccggggagguaguga
cgaaaaauaacaauacaggacucuuucgaggcccuguaauuggaaugagu
ccacuuuaaauccuuuaacgaggauccauuggagggcaagucuggugcca
gcagccgcgguaauuccagcuccaauagcguauauuaaaguugcugcagu
uaaaaagcucguaguuggaucuugggagcgggcgggcgguccgccgcgag
gcgagccaccgcccguccccgccccucucggcggcccgaagcguuuacuu
ugaaaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcag
cuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaac
ugaggccaugauuaagagggacggccgggggcauucguauugcgccgcua
gaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuug
ccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagacga
ucagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcgg
cggcguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuu
uggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauugac
ggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacacg
ggaaaccucacccggcccggacacggacaggauugacagauugauagcuc
uuucucgauuccgugggugguggugcauggccguucuuaguugguggagc
gauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaacua
guuacgcgacccccgagcggucggcgucccccaacuucuuagagggacaa
guggcguucagccacccgagauugagcaauaacaggucugugaugcccuu
agauguccggggcugcacgcgcgcuacacugacuggcucagcgugugccu
acccuacgccggcaggcgcggguaacccguugaaccccauucgugauggg
gaucggggauugcaauuauuccccaugaacgaggaauucccaguaagugc
gggucauaagcuugcguugauuaagucccugcccuuuguacacaccgccc
gucgcuacuaccgauuggaugguuuagugaggcccucggaucggccccgc
cgggggcccuggcggagcgcugagaagacggucgaacuugacuaucuaga
ggaaguaaaagucguaacaagguuuccguaggugaaccugcggaaggauc
auua
...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<....<<....<<<<<.............<<.....<<.<<
<.....>>>.>>......>>.........<<<<...<<<<........>>
>>...>>>><<..<<<<<...<......>..>>>>>......>>...<<<
<.<<<<......>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<
....<<<<<<<.........>>>>>>>>>>......>>>...<<<.<<<<
....>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....
>>.>...>>>>>>.........<<<....<<<<...>>>>..>>>..>..
.>>.>.....<..<...<<..<<....>>..>>.....>...>.....<<
..<...........>..>>.........<<<<<((......<<<<.....
<<..))>>.......>>>>.>>>>>..>>>>>>.>>>.........<.<(
(.....<.<<...<<<.<<.....<..<<<<<<<<<<<<<.<<<<....>
>>>....>>>>>>>>..>>>>>.><<.<.........>.>>...<<<<<<
.<.......<<...<.......>.<<<<.......>>>>...>>......
>.>>>..>>>........<.<<.<<<<<..................>>.>
>>.>>.>....>>....<<<<<<..<...<<<<..<<..<<<<<<<<...
<<<......>>>......>>>>>>>>..>>.......<<....>>...>>
>>..>..>>>.>>>...>>>...>>.>....<<<<<<<...<...<<<<.
<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<
<<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>...
..>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>
..........<<<<<.<....<<<<<<.......<<.<<<........>>
>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<..
..>>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<
<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..>.....
<<<<<.....>>>>>........>>>....>>>.>>>.....>>>>>>>.
....>.>>>>>...>>.>>>>.>>>.....<<.<<<........<.....
..<<<.<<<<....>>>>.>>>....>.........>>>.>>......<.
....<<<<<..........>>>>>.....>.....>>>>>.....<<<<<
<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<
<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.....
..................>>>>>...>>.>>>>..>>>.>>>>>>>>...
>>.>>>>...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj4 UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Resolution3.2 Å
Binding residue
(original residue number in PDB)
P24 K28 K56 H101 S112 V114 K115 K116 W117 Q118 M120 H124 R136 F138 R146 N148 Q149 I150 R151 Y155 Q157 H158 Q159 Q160 R162 R165 Q202 S203 I204 Y205 P206 K216
Binding residue
(residue number reindexed from 1)
P2 K6 K34 H79 S90 V92 K93 K94 W95 Q96 M98 H102 R114 F116 R124 N126 Q127 I128 R129 Y133 Q135 H136 Q137 Q138 R140 R143 Q180 S181 I182 Y183 P184 K194
External links
PDB RCSB:8pj4, PDBe:8pj4, PDBj:8pj4
PDBsum8pj4
PubMed
UniProtP61247|RS3A_HUMAN Small ribosomal subunit protein eS1 (Gene Name=RPS3A)

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