Structure of PDB 8he5 Chain O Binding Site BS01

Receptor Information
>8he5 Chain O (length=516) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIDDGDDAFYNARLNAWVTKRSQDEEEWFKPHPTKQDAILDDDYRLPGDV
YPALFDYQKTCVQWLWELYLQKVGGILGDEMGLGKTVQIISFIAGLHYTK
KLNKPVIVVCPATVLRQWCNEFHRWWPPLRVVILHAIGESRVKELIDSVF
TRGHVIITTYVGLRIYSKHLLKRDWGYAILDEGHKIRNPNSDISLTCKQL
RTPNRVILSGTPIQNNLTELWSLFDFIFPGRLGTLPVFQNQFAIPINVGN
LQVQVGYKCAVTLKDLISPYLLRRVPKKSEMVLFCKLTAPQHALYEKFLR
SDELSRILQGKRQVLYGIDILRKICNHPDLVDVHAKRRSKKDPTYGSASK
SGKMQVVKKLLELWKSQGHKTLLFTQTRQMLDILESFLERLNAKGAEEED
FVPFKFLRMDGTTSIGVRQSLVDVFNNDPSYNVFLLTTRVGGLGVNLTGA
NRVIIYDPDWNPSTDVQARERAWRLGQKKDVTIYRLMIAGSIEEKIYHRQ
IFKQFLTNKILKDPKQ
Ligand information
>8he5 Chain N (length=142) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gtggccgttttctgtctcgtgcctggtgtcttgggtgtaatccccttggc
ggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctagagc
tgtctacgaccaattgagcggcctcggcaccgggattctgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8he5 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
Resolution6.95 Å
Binding residue
(original residue number in PDB)		D478 V614 L615 S714 R799
Binding residue
(residue number reindexed from 1)		D192 V314 L315 S414 R499
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006338 chromatin remodeling
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8he5, PDBe:8he5, PDBj:8he5
PDBsum8he5
PubMed37120012
UniProtC4R198

[Back to BioLiP]