Structure of PDB 8eth Chain O Binding Site BS01 |
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| >8eth Chain 1 (length=1303)
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uugaccucaaaucagguaggacuacgcgcuaagcgcaggaaaagaaaaua
accaugauucccucaguaacgugaagcgggaaaagcucaaauuugaaauc
uggcaacauuucuuuuguuguccgaguuguaauuucaagaagcugcuuug
aguguagacgaucggucuaaguuccuuggaacaggacgucagagagggug
agaaccccgucuuuggucgauuggauaugccauauaaagcgcuuucgaag
agucgaguugugcagcucuaaauggguggucaucuaaagcuaaauauugg
cgagagaccgauagcgaacaaguagagugaucgaaagaugaaaagaacuu
ugaaaagagaguuaaauaguacgugaaauugcugaaagcauuggaaauca
gucuuaccugggugagaucaguagucucucgagacuaugcacucugaacc
ugugguaggucagcaucaguuuucgggggcggaaaaagaauaagggaagg
uggcuguuuauagcccuuguuguaauacguccacuggggacugaggacug
cggcuucgugccaaggaugcugacauaaugguuuucaauggcccguccac
ggaccaaggagucuagcaucuaugcgaguguuugggugaugaaaacccau
ccgcgaggugggaacgcccuggcgugcaccaucagagcauagcuguuggg
acccgaaagauggugaaccaucuaguagcugguuccugccgaagagcaga
aacucagaucaguuuuaaaugagaguuucuagugggccauuacuggcgau
gcgggccgaacgugagguuaaggugccggaauguacgcuagaaagguguu
aguuaacuagcccugggcgcuuaagcguacuacccauaccucaccgucug
gguuagcuuugagaagcucagacgaguaggcaggcguggagguuugugac
gaagccuugggcgugagccugggucgaacagccucuagugcagaucuugg
uggaaguagcagcgaaaccacagccugggggccaggucgucgcaauggua
auucaacuuaguacggaaccguugauucagaucauugguagagcuaucau
cugccggauaacggcugagccagaauccgugccagagcgacgauauguau
aaaaauagaggucucuccuguaucguagaagaugggcgaugguugaugaa
acggaaguguuuuauugacuuguccaugaaauuccagaauccauugcaua
cgacuuuaauguggaacgggguauuguagauuaagccuuuguucccaaga
uuu |
........................<<<<<<.>>>>>.>.........<<.
...>>..<<<<<......<<>>.....>>>>>..<<<..<<.......<<
.<<<<<<<.......>>>>>>>.>>.......>>....<<<<<.<<<<<.
.<<<<<..<<<<<<<<<.....<<<<......>>>>.((......<<<..
...))>>>......>>>>>>>>>..>>>>>.....>>>>>>>>.>>....
....<<<<<<..>>>>>>.....<<<<<..>>>>>..>>>..........
........................<<....>>...............<<<
<....>>>>.............................<<<<<<<<<<<<
.....<<<.<<<<.<<<.<<.<<<<<<<..>>>>>>>>>...>>>..>>>
>..>>>..<<<<<<<.<<<<<<<<<<<<<<<.......<<<<<<<<....
..<...>......>>>>>>>>......>>>>>.>>>>>>>>>>.......
.<<<.....>>>.....>>>>>>>....>>>>>>>>>>>>..<<<<..>>
>><<<<<<...<<<<<<<.<<<<<<..<<<...<<<<.......>>>>..
.>>>...<<<<..<<<<<..>>>>>...>>>>....>>>>>>.>>>>>>>
.<<.<...<<<<<<..>>>>>>......>.>>..<<<<<<.....<<<<<
<<<.....<<<.<<...>>>>>..>>>>>>.>>..<<<<....>>>>...
.<<<.>>>...<<<<<<<...<<<(((.....<<<<<<.<<..<<<.<<<
<<<..>>>>>>>>>.))).>>...>>>>>>.>>>...>>>>>>><<<<<<
<<<............>>>>>>>>>....>>>>>>..<<<<<<<<.<<...
...<<<<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>>>
><<.....<<.>>....>>....<<<<<...>>>>><<<<<<<..<<<<.
<.<<<<<......<>.....>>>>>.><<<<<...<<<<...>>>>..>>
>>>.<<<<....<<<<.>>>>....>>>>.>>>>..>>>>>>>.....<<
.......<<<<..>>>>....>>........<<<<<....<<<<<<<<<<
<<......>>>>>>>>>>>>..>>>>>.........<<<<<.<.......
......>.....<<<<<<<<<.<<<...>>>....>>>>.>>>>>...>>
>>> |
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| PDB | 8eth Chromatin localization of nucleophosmin organizes ribosome biogenesis. |
| Resolution | 3.8 Å |
Binding residue
(original residue number in PDB) | K6 K13 G18 R19 S22 K26 R38 S45 R50 A71 H73 F74 R75 A84 R86 G87 M88 H91 T93 A94 R95 V106 I109 P111 P112 D114 K115 Q116 R118 R126 V127 L130 K131 P132 R134 K149 Y150 L157 R161 K162 K164 S165 F168 Y169 K172 |
Binding residue
(residue number reindexed from 1) | K4 K11 G16 R17 S20 K24 R36 S43 R48 A59 H61 F62 R63 A72 R74 G75 M76 H79 T81 A82 R83 V94 I97 P99 P100 D102 K103 Q104 R106 R114 V115 L118 K119 P120 R122 K137 Y138 L145 R149 K150 K152 S153 F156 Y157 K160 |
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