Structure of PDB 8cqw Chain O Binding Site BS01

Receptor Information
>8cqw Chain O (length=116) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEDALKVVLRTSLVHDGLARGLREASKALSKREAQLCVLCDSVTEESIIK
LVEALCNEPEEKIPLIKVSDAKLLGEWAGLCQLDRDGNARKVVGASCVVV
KNWGADSDERNILLEH
Ligand information
>8cqw Chain B (length=1741) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguacccuacuuggauaaccguggu
aauucuagagcuaauacaugcuuaaaaucccgacuguuuggaagggaugu
auuuauuagauaaaaaaucaaugccuucgggcucuuugaugauucauaau
aacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauuuc
ugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaacg
gguaacggggaauaaggguucgauuccggagagggagccugagaaacggc
uaccacauccaaggaaggcagcaggcgcgcaaauuacccaaucccgacac
ggggagguagugacaauaaauaacgauacagggcccuuuugggucuugua
auuggaaugaguacaauguaaauaccuuaacgaggaacaauuggagggca
agucuggugccagcagccgcgguaauuccagcuccaaaagcguauauuaa
aguuguugcaguuaaaaagcucguaguugaaccuugggcuuggcuggccg
ggcguacuggacccagccgagccuuuccuucuggguagccgaaccaggac
uuuuacuuugaaaaaauuagaguguucaaagcaggccuuugcucgaauau
auuagcauggaauaauagaauaggacguuaugguucuauuuuguugguuu
cuaggaccaucguaaugauuaauagggacggucggggguaucaguauuca
guugucagaggugaaauucuuggauuuacugaagacuaacuacugcgaaa
gcauuuaccaaggacguuuucauuaaucaagaacgaaaguuaggggaucg
aagaugaucagauaccgucguagucuuaaccauaaacuaugccgacuagg
gaucgguuguuguucuuuuauugacgcaaucggcaccuuacgagaaauca
aagucuuuggguucuggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggaguggagccugcggcuuaauuugacu
caacacggggaaacucaccagguccagacacaauaaggauugacagauug
agagcucuuucuugauuuugugggugguggugcauggccguucuuaguug
guggagugauuugucugcuuaauugcgauaacgaacgagaccuuaaccua
cuaaauagugcugcuagcauuugcugguauagucacuucuuagagggacu
aucgauuucaagucgauggaaguuugaggcaauaacaggucugugaugcc
cuuagacguucugggccgcacgcgcgcuacacugacggagccagcgagua
uaagccuuggccgagaggucugggaaaucuugugaaacuccgucgugcug
gggauagagcauuguaauuguugcucuucaacgaggaauuccuaguaagc
gcaagucaucagcuugcguugauuacgucccugcccuuuguacacaccgc
ccgucgcuacuaccgauugaauggcuuagugaggccuccggauugguuua
uucuggaaccgagaagcuggucaaacuuggucauuuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucau
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<............<<.....<..<<..
.....>>..>......>>........<<<<<..<<....>>..>>>>><.
..<<<<<<.......((((((.<<<....>>>..............>>>>
>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>>>>..>
>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>
>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..........>>
>.>>.<.<<....>>.>...>>>>>>.........<<<....<<<<...>
>>>..>>>..>....>.>.....<<<<<<<<.<<<<....>>>>.>>>>>
.>>>......<<..<...........>..>>.........<<<<<((...
...<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>>.
........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<.....
..............>>>>>>>>>>.....<<<<...........>>>>..
..<<<<<.<<.......<<...<.......>..<<<....>>>....>>.
.....>>.>>..>>>.........<<<..<<<<<<<<......)))))).
..>>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<.<...<<<......>>>......>.>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<..<<........>>.>>>>>>>>..>>>...<<..]]>>.
..>>.....>>>.>>>.<<<......<<<<....>>>>....>>>..]]]
].}<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<...
.....>>..........<<<<<......<<<<<........<<.<<<...
.....>>>.>>......>>>>>...<<.<<<..<<.<<<<<.....<<<.
<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..
<<<<..<<<<.<<<<<<<....>>>>>>>....>>>>..>>>>.>>....
<<<<<<.....>>>>>>.......>>>>>.....>>.>>>.....>>>>>
>>.......>>>>>...>>.>>>>.>>>.....<<<<<<<......<<..
....<<<.<<<<....>>>>.>>>....>>.......>>>>>>>......
<....<<<<<<..........>>>>>>....>.....>>>>>>....<<<
<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<.
.<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<..<...<<<<<...
.......>>>>>...>..>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cqw Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.05 Å
Binding residue
(original residue number in PDB)
R43 G44 L45 R46 E47 K50 T67 L103 K114 G117 A118 S119
Binding residue
(residue number reindexed from 1)
R20 G21 L22 R23 E24 K27 T44 L80 K91 G94 A95 S96
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