Structure of PDB 7w4k Chain O Binding Site BS01

Receptor Information
>7w4k Chain O (length=217) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAGGALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHKAAAVLPV
LDLAQRQNGWLPISAMNKVAEILQVPPMRVYEVATFYTMYNRKPVGKYHI
QVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVN
APMVQINDNYYEDLTPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLT
SLTEPPKGPGFGVQAGL
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7w4k Chain O Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7w4k The coupling mechanism of mammalian mitochondrial complex I.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C135 P139 C140 C176 L177 G178 A179 C180
Binding residue
(residue number reindexed from 1)		C103 P107 C108 C144 L145 G146 A147 C148
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:7w4k, PDBe:7w4k, PDBj:7w4k
PDBsum7w4k
PubMed35145322
UniProtA0A287BG40

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