Structure of PDB 7w1t Chain O Binding Site BS01

Receptor Information
>7w1t Chain O (length=217) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAGGALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHKAAAVLPV
LDLAQRQNGWLPISAMNKVAEILQVPPMRVYEVATFYTMYNRKPVGKYHI
QVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVN
APMVQINDNYYEDLTPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLT
SLTEPPKGPGFGVQAGL
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7w1t Chain O Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7w1t The coupling mechanism of mammalian mitochondrial complex I.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C135 T137 P139 C140 C176 L177 A179 C180
Binding residue
(residue number reindexed from 1)		C103 T105 P107 C108 C144 L145 A147 C148
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:7w1t, PDBe:7w1t, PDBj:7w1t
PDBsum7w1t
PubMed35145322
UniProtA0A287BG40

[Back to BioLiP]