Structure of PDB 7ozo Chain O Binding Site BS01

Receptor Information
>7ozo Chain O (length=257) Species: 9825 (Sus scrofa domesticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQ
IDANSSVLHDEFIAHRLGLIPLTSDDIVDKLQYSRDCTCEEFCPECSVEF
TLDVRCNEDQTRHVTSRDLISNSPRVIPVTSDDILIVKLRKGQELRLRAY
AKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDED
ESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLS
HEIQSDV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7ozo Chain O Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ozo Structure of an inactive RNA polymerase II dimer.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
C88 C90 C94 C97
Binding residue
(residue number reindexed from 1)
C87 C89 C93 C96
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7ozo, PDBe:7ozo, PDBj:7ozo
PDBsum7ozo
PubMed34530439
UniProtA0A481DF93

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