Structure of PDB 7of5 Chain O Binding Site BS01

Receptor Information
>7of5 Chain O (length=152) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISHGRVFRRMGLGPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEK
LIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYKDQTGGYTRML
QIPNRSLDRAKMAVIEYKGNCLPPLPLPRRDSHLTLLNQLLQGLRQDLRQ
SQ
Ligand information
>7of5 Chain A (length=1389) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaaccccaccuuacuaccaaaccuuagccaaacca
uuuacauaaaguauaggcgauagaaauugauggcgcaauagauauaguac
cgcaagggaaagaugaaaaacaagcauaauauagcaaggacuaaccccua
uaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagagccaa
agcuaagacccccgaaaccagacgagcuaccuaagaacagcuaaaagagc
acacccgucuauguagcaaaauagugggaagauuuauagguagaggcgac
aaaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguu
caacuuuaaauuugcccacagaacccaaauccccuuguaaauuuaacugu
uaguccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagag
agaguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauua
agaaagcguucaagcucaacacaaaaaucccaaacauauaacugaacucc
ucacacccaauuggaccaaucuaucacccuauagaagaacuaauguuagu
auaaguaacaugaaaacauucuccuccgcauaagccugcgucagcugaca
auuaacagcccaauaucuacaaucaaccaacaagucauuauuacccucac
ugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaa
ggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuag
caucaccaguauuagaggcaccgccuuccuuaaauagggauggcuccacg
aggguucagcugucucuuacuuuuaaccagugaaauugaccugcccguga
agaggcgggcauaacacagcaagacgagaagacccuauggagcuuuaauu
uauuaaugcaaacaccugcauuaaaaauuucgguuggggcgaccucggag
cagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaagcg
aaccucaauugauccaauaacuugaccaacggaacaaguuacccuaggga
uaacagcgcaauccuauucuagaguccauaucaacaauaggguuuacgac
cucgauguuggaucaggacaucccgauggugcagccgcuauuaaagguuc
guuuguucaacgauuaaaguccuacgugaucugaguucagaccggaguaa
uccaggucgguuucuaucuacuuuaauuccucccuguacgaaaggacaag
agaaauaaggccuacuucacaaagcgccuucccccguaaaugauaucauc
ucaacuuaguauuauacccacacacccaagaacaggguu
<<<.......<<<<..............................<.....
.>...........<<.....>>.........>>.>>.............<
<....>>...............>>>...........<<<.......>>>.
..<.<........>.>.<<<<<<.........<<<.<<..<<....>>..
.>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<.....>>>
...<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<....
...>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>
><<<.<<<<<<<<<<.....<<.......>>.....>>>>>>>>>>..>>
>.<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<
.<<<...<..............<....<<<.........>>>....>...
....<<<......>>>..........................>...>>>>
>>........>>>>>>...<<<<<......>>>>>.........>>>>>>
.......<<..<<<....>>><<<<..<<<<........<<<<..>>>>.
.....<<<...<<<<.......................>>>>.......>
>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.<
<.........<......<<<<<<..<<<.........>>>...<<<<<<.
............>>>>>>....<<<.<<<<.....>>>>..>>>....>>
.>>>>.....>..>>.>>>>>>>>>>>>.>>...........<<<<<...
.....>>>>>.......<<..<<<.<<......<<<<.<<<<<<..<<<<
<.<<<<<<<<......>>>>>>>>>>>>>..<<<<.....>>>><<<<<<
...........>>>>>>..<<.....<<<..<<<<.....>>>>..>>>.
...>>.........<<<....>>>............>>>>..>>>>>>..
.....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>
......<<<<<<.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<
<<<.....>>>>>.....>>>>>..>...>>>.>>>...<<<<<<<....
>>>.>>>>....>>..>>>.>>...<<<.<<<.................>
>>.>>><<<<<...<<<....>>>.>>>>>......<<<...........
.....>>>...............<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7of5 Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		I9 S10 H11 G12 R13 V14 R16 R17 L20 G21 H27 R30 N31 L32 H39 I42 A47 R48 T81 E82 D116 R117 A118 K119
Binding residue
(residue number reindexed from 1)		I1 S2 H3 G4 R5 V6 R8 R9 L12 G13 H19 R22 N23 L24 H31 I34 A39 R40 T73 E74 D108 R109 A110 K111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7of5, PDBe:7of5, PDBj:7of5
PDBsum7of5
PubMed34135319
UniProtQ9NRX2|RM17_HUMAN Large ribosomal subunit protein bL17m (Gene Name=MRPL17)

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