Structure of PDB 7et3 Chain O Binding Site BS01

Receptor Information
>7et3 Chain O (length=69) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLLHTFWRLPVAVFFEPHEENVLRCPERVLRRLLEDAAVTMDRVRKRYLR
QELRDLGHRVQTYCEDLEG
Ligand information
>7et3 Chain H (length=20) Species: 10359 (Human betaherpesvirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LRQLAQSVQDTIQHMRFLYL
Receptor-Ligand Complex Structure
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PDB7et3 Structural basis for genome packaging, retention, and ejection in human cytomegalovirus.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		Y60 Q63
Binding residue
(residue number reindexed from 1)		Y48 Q51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019072 viral genome packaging
GO:0019073 viral DNA genome packaging
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019028 viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7et3, PDBe:7et3, PDBj:7et3
PDBsum7et3
PubMed34315863
UniProtP16726|CVC2_HCMVA Capsid vertex component 2 (Gene Name=CVC2)

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