Structure of PDB 6ysi Chain O Binding Site BS01

Receptor Information
>6ysi Chain O (length=109) Species: 575584 (Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEVTAKLRGAAISAQKARLVADLIRGKSVAHALNILNFSNKKAAVLVKKA
LESAIANAEHNNSLDVDDLKVSTIYVDEGMSLKRIMPRAKGRADRITKRT
CHITVKVGV
Ligand information
>6ysi Chain 1 (length=2672) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaaguaauuaagugcaugugguggaugccuuggcagucagaggcgaug
aaagacgugauagccugcgaaaagcuccggggaggcggcaaauauccuuu
gauccggagaugucugaaugggggaacccaccuacuuuaagguagguauu
gcaacaugaauacauaguguugcaaggcgaacgaggggaagugaaacauc
ucaguacccuuaggaaaagaaaucaauugagauucccucaguagcggcga
gcgaacggggaucagcccauuaaguuauguguguuuuaguggaacgcucu
gggaagugcgaacguagagggugauauucccguacacgaaagggcacaca
uaaugaugacgaguagggcgaggcacgugaaaccuugucugaauaugggg
ggaccauccuccaaggcuaaauacuccugacugaccgauagugaaccagu
accgugagggaaaggcgaaaagaaccccugugaggggagugaaauagauc
cugaaaccgcaugcauacaagcagugggagcaccuuuguggugugacugc
guaccuuuuguauaaugggucagcgacuuauauucaguagcgagguuaac
cguauaggggagccguagagaaaucgagucuuaauagggcguuuaguugc
uggguauagacccgaaaccaggcgaucuauccaugagcagguugaagguu
ggguaacacuaacuggaggaccgaacccacugucguugaaaagccagggg
augacuuguggauaggggugaaaggcuaaucaagccuggugauagcuggu
ucuccccgaaagcuauuuagguagcgccucggacgaauaccauagggggu
agagcacuguuucggcuaaccgaugcaaacuccgaauaccuaugaguacu
auccgggagacagacugcgggugcuaacguccguagucaagaggaaaaca
auccagaccgccagcuaaggccccaaaaucauaguuaagugggaaacgau
gugggaaggcaagucggccugcgcggaagauguaacggggcuaaaacuau
gugccgaagcugcggauguauacuuuguauacgugguaggggagcguucu
guaagccgaugaagguguguugagaagcaugcuggagguaucagaagugc
gaaugcugacgugaguaacgacaaaacgggugaaaaacccguucgccgaa
agaccaaggguuccaguccaacguuaaucggggcugggugagucgacccc
uaaggcgaggccgaaaggcguagucgaugggaaaaugguuaauauuccau
uacuucuguguaaugcgaugagaggacggagaaggcuaaaucagccuggc
guugguuguccaggugaaaggauguaggcauguaucuuaggcaaauccgg
gguacucuaugcugagaucugaaagugguugaugccaugcuuccaggaaa
agucucuaagcuucaguuacacaggaaucguacccgaaaccgacacaggu
ggucaggucgaguagaccaaggcgcuugagagaacucugcugaaggaacu
aggcaaaaugguaccguaacuucgggagaagguacgcuguuguuggugau
ugagcugacgacagccgcagaaaccaggccgcugcaacuguuuauuaaaa
acauagcacucugcaaacacgaaaguggacguauagggugugaugccugc
ccggugcuggaagguuaauugaugggguuagcguaagcgaagcucuugau
cgaagccccaguaaacggcggccguaacuauaacgguccuaagguagcga
aauuccuugucggguaaguuccgaccugcacgaauggcauaaugauggcg
gcgcugucuccagcagaggcucagugaaaucgaaaucgcugugaagaugc
aguguacccgcggcuagacggaaagaccccgugaaccuuuacugcagcuu
gacacugaacugguucuaacucugucccgugauccgggacgaggaccgug
ucugguggguaguuugacuggggcggucuccuccuaaagaguaacggagg
aguacgaaggugcgcucagcguggucggaaaucacgcguagaguauaaag
gcaaaagcgcgcuuaacugcgagacccacaagucgagcagguacgaaagu
aggucuuagugauccggugguucuguauggaagggccaucgcucaacgga
uaaaagguacucuggggauaacaggcugauaccgcccaagaguucauauc
gacggcgguguuuggcaccucgaugucggcucaucucauccuggggcuga
agcaggucccaaggguauggcuguucgccauuuaaagagguacgcgagcu
ggguuuagaacgucgugagacaguucggucccuaucuaccgugggcgcug
gaaauuugagaggaucugcuccuaguacgagaggaccagaguggacgaac
cucugguguaccgguugugacgccagucgcaucgccggguagcuauguuc
ggaagggauaaccgcugaaagcaucuaagcgggaagccuaccucaagaua
agauuucccuaggacuuuauguccucuaaagagccguucgagacuaggac
guugauagguuggauguggaagcauagugauaugugaagcugaccaauac
uaauugcucgugaggcuugacu
<<<<<<<......<<<<<<<<<<<.....<<.<<<<<<<<<<<<<<....
..<<<<<<.[..(((.>>>.....<<<<<<<..<<.)))...]..>>...
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...<<<......<<<<<<<<<<<<<<.<<<...<<<.<.
.....>.>>>((......<<<.....))>>>...>>>...>>>>>>>>>>
>>>>...........<<<<<<<<.........>>>>>>>>......<<<<
<..((((>>>>>..>>>......>>.>>>>>>>.>>>.............
.<<....>>....>>.........<<<<.....>>>>.............
.....>>>>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>
...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<
<.....>>...>>>...<<....>>..<<<<.....>>>>.....>>>>>
>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<<...<<<<
<<......>>>>>>.>...>>>...<<<.<<<.<........>.>>>>>>
....>>>>>>>>>...<<<.....>>>......>>>>>>...>..>.>>.
.<<<<<<....<<<<<....>>>>>.<<<<<<<....<<<<<<<<<....
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.>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>....<<<.....
.>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<..
<<<<<..<<....>>..>>>>>.>>...........)))......>>>>>
>.>>>...>>>>>>><<<<<<<<...>>>>>>>>....>>>>>>..<<<<
<...<<<......<<<<<<<<....>>>>>>>>...>>>..>>>>>....
....>>>>>><......<<.....<<<<<<.......>>>>>><<<<...
.<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<.<<<
...<<<...<<<....>>>...>>>...>>>..<<<<<........>>>>
>))<<<<<<<<<<<<<...<<<<....<<<<..<<<..<<<<<<<<<<<.
..[[[[...>>>>>>....<<<<...<<<<.<<<<<<..<<.....>>.>
>>>>>....>>>>...>>>>.....>>>>>...>>>...>>>>.......
..>>>>...>>....>>>>>>>>>>>.>>>..>>.....<<......>>>
>>>>.<<<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<.....
..........<<<<<...............>>>>><<<<<<<<<<<<...
...>>>>>>>>>>>>............<<<<<<<<<..<<<.........
>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<
<..<<<<<<<..<<<<...<...<<<<<..<<....>>...>>>>>.>..
...>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<...
........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>>>
>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<........>
>>>>..<<<<<<<.<<<<.<<......<<<<.<<<<<<..<<<<..<<<.
<<<<<.<<<<..>>>>...<<<.<<<<<<.....>>>>>>>>>....>>>
>>.>>>...>>>>..<<<<.....>>>><<<<<<...........>>>>>
>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((
>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<....>>
>.>>)))]......<<<<<<<.<<..))))..>>>>>>>>>.........
....>>>>..>>>>>>.......<<<<...<<<<<<...<<.......>>
...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<..
....>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>
.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>>>>>....<
<<<<<<...<<<<..<<<<<<.................>>>>>>.<<<<<
...<<<<...<<<<<<<<<<<]]]]>>>>>>..>>>>>...>>>>.>>>>
>...<<<....<<<<<...........>>>>>....>>>.>>>>......
.>>>>>>>..<<<<<.....>>>>><....<<<<<<<<<.......>>>>
>....<<<<<<<<..<<....<<<<<....>>>>>...>>...>>>>>.>
>>...>>>>..>..>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ysi Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K7 L8 R9 S14 Q16 K17 R19 R26 K42 K43 K50 S54 A57 N58 H61 N62 D78 E79 M81 R85 P88 R89 A90 K91 G92 R93 A94 D95 I97 T98 K99 R100 H103
Binding residue
(residue number reindexed from 1)		K6 L7 R8 S13 Q15 K16 R18 R25 K41 K42 K49 S53 A56 N57 H60 N61 D77 E78 M80 R84 P87 R88 A89 K90 G91 R92 A93 D94 I96 T97 K98 R99 H102
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ysi, PDBe:6ysi, PDBj:6ysi
PDBsum6ysi
PubMed32857965
UniProtD0CD02

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