Structure of PDB 6spd Chain O Binding Site BS01

Receptor Information
>6spd Chain O (length=115) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVKKETRLRRARKARLKMRELETVRLCVYRSSQHIYAQVIAADGGKVLAS
ASTLDKDLREGATGNIDAAKKVGQLVAERAKAAGVTQVAFDRSGFKYHGR
VKALADAAREGGLEF
Ligand information
>6spd Chain A (length=2851) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucaagugaagaagcgcauacgguggaugccuuggcagucagaggcgaug
aaagacgugguagccugcgaaaagcuucggggagucggcaaacagacuuu
gauccggagaucucugaaugggggaacccaccuaggauaaccuagguauc
uuguacugaauccauaggugcaagaggcgaaccaggggaacugaaacauc
uaaguacccugaggaaaagaaaucaaccgagauucccuuaguaguggcga
gcgaacggggauuagcccuuaagcuauuuuagcggaacgcucuggaaagu
gcggccauagugggugauagccccguacgcgaaaggaucuuugaagugaa
aucaaguaggacggagcacgagaaacuuugucugaacauggggggaccau
ccuccaaggcuaaauacuacugacugaccgauagugaaccaguaccguga
gggaaaggcgaaaagaaccccggagaggggagugaaauagaccugaaacc
guaugcguacaagcagugggagccuacuuguuaggugacugcguaccuuu
uguauaaugggucagcgacuuauauucaguggcaagcuuaaccguauagg
guaggcguagcgaaagcgagucuuaauagggcguagucgcuggguauaga
cccgaaaccgggcgaucuauccaugagcagguugaagguuagguaacacu
gacuggaggaccgaacccacucccguugaaaagguaggggaugacuugug
gaucggagugaaaggcuaaucaagcucggagauagcugguucuccucgaa
agcuauuuagguagcgccucauguaucacucugggggguagagcacuguu
ucggcuagggggucaucccgacuuaccaaaccgaugcaaacuccgaauac
ccagaagugagcaugggagacacacggcgggugcuaacguccgucgugaa
aagggaaacaacccagaccgccagcuaaggucccaaaguugugguuaagu
gguaaacgaugugggaaggcuuagacagcuaggagguuggcuuagaagca
gccacccuuuaaagaaagcguaauagcucacuagucgagucggccugcgc
ggaagauguaacggggcaaccacacaccgaagcugcgggugucacguaag
ugacgcgguagaggagcguucuguaagccugugaaggugaguugagaagc
uugcuggagguaucagaagugcgaaugcugacaugaguaacgacaauggg
ugugaaaaacacccacgccgaaagaccaaggguuccugcgcaacguuaau
cgacgcaggguuagucgguuccuaaggcgaggcugaaaagcguagucgau
gggaaacagguuaauauuccuguacuucugguuacugcgauggagggacg
gagaaggcuaggccagcuuggcguugguuguccaaguuuaaggugguagg
cugaaaucuuagguaaauccgggguuucaaggccgagagcugaugacgag
ucguagaugacgaagugguugaugccaugcuuccaagaaaagcuucuaag
cuucagguaaccaggaaccguaccccaaaccgacacagguggucggguag
agaauaccaaggcgcuugagagaacucgggugaaggaacuaggcaaaaug
gcaccguaacuucgggagaaggugcgccggcuagugaaaagcucuggcug
gucgaagauaccaggccgcugcgacuguuuauuaaaaacacagcacucug
caaacacgaaaguggacguauagggugugacgccugcccggugccggaag
guuaauugaugggguuagcgcaagcgaagcucuugaucgaagccccggua
aacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucgg
guaaguuccgaccugcacgaauggcguaacgauggcggcgcugucuccac
ccgagacucagugaaauugaaaucgcugugaagaugcaguguauccgcgg
cuagacggaaagaccccgugaaccuuuacuguagcuuugcacuggacuuu
gagccugcuuguguaggauaggugggaggcuuugaagcguggacgccagu
ucgcguggagccauccuugaaauaccacccuggcaugcuugagguucuaa
cucugguccguaauccggaucgaggacaguguauggugggcaguuugacu
ggggcggucuccuccuaaagaguaacggaggaguacgaaggugcgcucag
accggucggaaaucggucgcagaguauaaaggcaaaagcgcgcuugacug
cgagacagacacgucgagcagguacgaaaguaggucuuagugauccggug
guucuguauggaagggccaucgcucaacggauaaaagguacuccggggau
aacaggcugauaccgcccaagaguucauaucgacggcgguguuuggcacc
ucgaugucggcucaucacauccuggggcugaagccggucccaaggguaug
gcuguucgccauuuaaagugguacgcgagcuggguuuagaacgucgugag
acaguucggucccuaucugccguggacguuugagauuugagaggggcugc
uccuaguacgagaggaccggaguggacgaaccucuggguuccgguuguca
cgccaguggcauugccggguagcuauguucggaaaagauaaccgcugaaa
gcaucuaagcgggaaacuugccucaagaugagaucucacugggaacuuga
uuccccugaagggccgucgaagacuacgacguugauaggcugggugugua
agcguugugaggcguugagcuaaccaguacuaaugcccgugaggcuugac
c
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<....(((.>>>.....<<<<<<<...<.))).....>.....
..>>>>>>>...>>>....<<<....>>><<<<<<<....>>>>>>>.<<
<<<<<<<.........>>>>>>>>>.>>...<<<<<<.....<......>
......>>>>>.>.........<<....>>...<<<<<.....<<.....
>>....>>>>>...(((........<<<<..<<<...<<<.<......>.
>>>((......<<<.....))>>>...>>>....>>>>............
........<<<<<<<<.........>>>>>>>>......<<<<<..<<<<
>>>>>..)))......]].>>>>>>>.]]...............<<....
>>....]].........<<<<.....>>>>............}....>>>
>>>>>>>>.......<<<<..<<<<<.....>>>>>..>>>>...<.<..
......>.>.<<<<<<....<<<<<<<<<<<<<..<<<...<<.....>>
...>>>...<<....>>..<<<<<...>>>>>...>>>>>>>>>>>>>..
<<.<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>
>>>>.....>>>...<<<.<<.<<........>>.>>>>>....>>>>>>
>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<...
.<<<<<....>>>>>.<<<<<<<<.....<<<<<<.....<<<...<<<.
<<<<...<..<<<.......>>>...>...>>>>.>>>..>>.>.....>
>>>>..>...>>>>>>>.>...<<<<<<<<<<......>>>>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<..<<........<<<<<..<...<<<.........
>>>...>.........<<<......>>>..>>>>>....>>..>>>>>.>
>...........)))...>>>>>>.>>>...>>>>>>><<<<<<......
>>>>>>....>>>>>><.<<<<<...<<<......<<<<<<<<....>>>
>>>>>...>>>..>>>>>..>.....>>>>>><......<<.....<<<<
<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....
>>.>>>>>>....((<<<<<<<...<<<...<<<....>>>...>>>...
>>>..<<<<<........>>>>>))<<<<<<<<<<<.<...<<<<....<
<<<..<<<..<<<<<<<<<<<....(((...>>>>>><<..<<<....<<
<.<<<<<<<..<<.....>>.>>>>>>>...>>>....>>>...>><..<
<<<....>>>>...>>>>>>...>>>...>>>.>........>>>>...>
.....>>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<<<.
....>>>>..>>>>..<<<<....<<<<<<<<.<<...............
<<<<<....<<..>>.....>>>>><<<<<<..<<.....>>....>>>>
>>............<<<<<<<<<..<<<.........>>>..<<<<<<<.
....<<<....>>>.......>>>>>>>.<<<<<.<<<..<<<<<<<..<
<<........<<<<<<.<<....>>..>>>>>>........>>>>>>>>.
.>>>>><<<<<.........>>>>>........<...........<<<<<
.......>>>>>.....>....>>>>>..>>.>>>>>>>.....>>.>>>
>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<
<.(((.[[......<<<<.[[<<<<..<<<<<.<<<.<<<<<.<<<<<<<
<<<<.<<<<...........<<<<<...........<.<.<<<<....>>
>>.>.>..................>>>>>..>>>>.>>>>>>>>>>>...
<<<.<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..<<<<
.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<
<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<
<..<<<......>>>..>>>>.<<<....>>>.>>)))]......<<<<<
<<.((..>>>>..))>>>>>>>.............>>>>..]]>>>>...
....<<<<...<<<<<<...<<.......>>...>>>>>>....>>>.>.
......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<
<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>
>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<
<<<...............>>>>>>>.<<<<<...<<<...<<<<<<<<<<
.)))..>>>>>..>>>>>....>>>.>>>>>...<<<.<..<<<<<....
.......>>>>>...>>>>.>>>>.......>>>>>>>..<<<<<.....
>>>>>.....<<<<<<<<<.......>>>>>....<<<<<<<<..<<...
..<<<......>>>....>>...>>>>>.>>>..>>>>.....>>>>>>>
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spd Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution3.28 Å
Binding residue
(original residue number in PDB)
R10 R13 K18 F91 R93 Y98 R110
Binding residue
(residue number reindexed from 1)
R9 R12 K17 F90 R92 Y97 R109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6spd, PDBe:6spd, PDBj:6spd
PDBsum6spd
PubMed31611393
UniProtE2RXU0

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