Structure of PDB 6n7x Chain O Binding Site BS01

Receptor Information
>6n7x Chain O (length=74) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVPPINCIFNFLQQQTPVTIWLFEQIGIRIKGKIVGFDEFMNVVIDEAVE
IPVEKGTPLGKILLKGDNITLITS
Ligand information
>6n7x Chain R (length=308) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaagauaucagaggaaaguccucugaucaaacaugcgcuuccaauaguag
aaggacguuaagcauuuaucauugaacuaguucauugaagucauugaugc
aaacuccuuggucacacacggcgcggaaggcguguuugcugacguuccau
ucccuuguuucaaucauugguuaacugauuuuuggggcccuuuguuucuu
cugccuggagaaguuugacaccaaauauugguguuaggggagcuggggcc
uuucaaaauuuuggaaggucuugguaggaacggguggaucuuauaauuuu
ugauuuau
<<<<<.<<<<<<<<.....>>>>>>>><<<<<<<<<.<<<<<........
<<<<<.<<<..<<<<.<.<<<.<<<<<..>>>>>.>>>.......>>>>>
.>>>>>>>>...............>>>>>>>>>>>>>><<<.<<<<<<..
<<<<<.<<<<<<<..<<<<<<..>>>>>>..>>>>>>>((.......<<<
<<....))>>>>>...<<<<<<<<...>>>>>>>>.>>>>><<<<<<<<<
<<<<<<<<>>>>>>>>>>>>>>>>>.>>>>>>..>>>.>>>>>.......
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n7x CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Q34 F49 N51 K83
Binding residue
(residue number reindexed from 1)		Q25 F40 N42 K65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:1990935 splicing factor binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0034715 pICln-Sm protein complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071004 U2-type prespliceosome
GO:0071011 precatalytic spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n7x, PDBe:6n7x, PDBj:6n7x
PDBsum6n7x
PubMed29051543
UniProtQ12330|RUXE_YEAST Small nuclear ribonucleoprotein E (Gene Name=SME1)

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