Structure of PDB 6f44 Chain O Binding Site BS01

Receptor Information
>6f44 Chain O (length=534) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVRELVEKIDG
MDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHILLYSGL
IIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTSDSMKY
TISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNSPLSDL
KKRSQAKMNAKTDFAKIINKPNELSQILTVDPKTSLRIVKPTVSLTINLD
RFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSPKIRDPLTQTGL
LQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPSASLINSHLKILAS
SNFPFLNETKPGVYYVPYSKLMPVLKSSVYEYVIASTLGPSAMRLSRCIR
DNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPRTADRSASRA
VFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLLKKANRDDLL
PSELNQLKMVNERELNVFARLSRLLSLWEVFQMA
Ligand information
>6f44 Chain Y (length=44) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
actattgcgaaaaaaacatttatttatagtagccgaaaatagtg
Receptor-Ligand Complex Structure
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PDB6f44 Molecular mechanism of promoter opening by RNA polymerase III.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		K520 R561
Binding residue
(residue number reindexed from 1)		K408 R449
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6f44, PDBe:6f44, PDBj:6f44
PDBsum6f44
PubMed29345638
UniProtP32349|RPC3_YEAST DNA-directed RNA polymerase III subunit RPC3 (Gene Name=RPC82)

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