Structure of PDB 6eu0 Chain O Binding Site BS01

Receptor Information
>6eu0 Chain O (length=550) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVRELV
EKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHIL
LYSGLIIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTS
DSMKYTISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNS
PLSDLKKRSQAKMNAKTDFAKIINKPNELSQILTVDPKTSLRIVKPTVSL
TINLDRFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSPKIRDPL
TQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAELHSASLI
NSHLKILASSNFPFLNETKPGVYYVPYSKLMPVLKSSVYEYVIASTLGPS
AMRLSRCIRDNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPR
TADRSASRAVFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLL
KKANRDDVKGRENELLLPSELNQLKMVNERELNVFARLSRLLSLWEVFQM
Ligand information
>6eu0 Chain R (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttttcggctactataaaaaaatgtttttttcgttcgcgaagtaacccttc
g
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6eu0 Structural basis of RNA polymerase III transcription initiation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
S233 D234
Binding residue
(residue number reindexed from 1)
S203 D204
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6eu0, PDBe:6eu0, PDBj:6eu0
PDBsum6eu0
PubMed29345637
UniProtP32349|RPC3_YEAST DNA-directed RNA polymerase III subunit RPC3 (Gene Name=RPC82)

[Back to BioLiP]