Structure of PDB 5t2a Chain O Binding Site BS01 |
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| >5t2a Chain A (length=1603)
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agaccugaguguggcaggacuacccgccgaacuuaagcauauuacucagc
ggaggaaaagaaaacaaccgugauucucucagugagcggcgagcgaagag
ggaacgaacucguugccgaaucgggucuuacaaggccuugaguuguggca
caaauaucugguuggugcaggaguggcgaaauucaagcgcaaagcaaacc
cguugcugaauacaacccuucaugugaguauugagccaaagaagguguua
gcccauugagccauaaaccugagcgccucaugaagcgaguagcacuguuu
gggaaugcagugucaaguuggcagguauuugucugccaaaguuaaauaca
gaguaggaagaccgauagcgaacaaguagcgugagcgaaaguuugaaaag
cacuuuggaaagagagugaaauagaaccugaagucgugacaaagacaaug
gaaguaccuccauuucaacggccagaaccagcccuacugcauuauccugu
cgggggucaaaauccggcgggcaaaagugcaagaauuuugggucuuggug
aaaugagcggaguauuugagcugugcacggccgcacgcacugguuucuuc
uccgugaugcuccauguuggcgaugaaauggggugcccccacccgucuug
aaacacggaccaaggagucaaacagacgcgcaagggaggagauaugguug
ccaguacuucucucguacugaaagggagaugcaauaugcaucuguggugu
gcacacgucauuugcccaacaccgaccggcccuggguugcguuggagugu
gccuguuuggacccgaaagguggugaacuaugccugaacaaggugaagcc
cggggaaacccagguggaggccuguagcgaugcugacgugcaaaucgcuc
guaugauuuggguaucggagcgaaagacucaucgaaccaccuaguagcug
guucacaucgaaguuucccucaggauagcuggugcuaguagaaguauugu
gcgguaaagcaaaugauuagagggaccuauucucaaacuuuaaaugugca
aacaaaccgugccuuagccaacugcaaggccggaaagaaaagaauuagag
gcaccaagugggccuucuucgguaagcggagcaggcgaugcggaaugaac
cgcuuagggauauguggcgucaaaacuuaugggcucauucucgauacgug
aaaaggguguugguggauaaauccaccggccccgaaaauggaugacgcuu
aagcccaauuagugguugcccauuauuccuuugguaagggcggaaacaaa
cggagaaaguguagcccuuccgauguagauguggccuggagguuaggacg
aagcuuauggcgugagccuaagauggaccggccucuagugcagaucuugg
uuggcguagcaaagaucuaacggagauauacaacaugcaacguuggauac
uggagcggggaaggauuucgugccaacggcacucguacacgaguuguucg
gaaacugagcacaacguuauaucguuuuguuaggaaagugaagguacuga
aaaggggcaacagagaaccugggauuauauuccaaaaagaaauugcaugu
ggg |
......................<<<<<......<......>.......>>
>>.>.........<<....>>..<<<<<<......<<.....>>....>>
>>>>...<<<...<<<<...<<<<<<<......>>>>>.>>.....>>>>
..........<..<<....<<....<......<<<<......<<<<....
...>>>>.....<<........>>......>>>><<.......((.....
>>)).......>......>>......>>>............<<<<<<<..
......>>>>>>>......<<<<<........>>>>>..>>>........
............................<<....>>..............
..<<<<....>>>>..................................((
(..<<<<<<.<<<<<<..((.<<<<.<<<<<<<<....<<<<<..<<<<<
<<<<........>>>>>>>>>...>>.>>>.........>>>>..>>>>.
.......<<<<<.....<<...<<<..<<..>>....>>>...>.>...>
>>>>.....<<<<...>>>>))..>>>>>>>>>>>>..))).<<<<....
....>>>><<<<<<....<<<<<<<.<<<<<..<<<...<<.<.......
.....>>>...>>>...<<....>>..<<<<<.....>>>>>...<<<<<
...<<.<<.>>.>>....>>>>><<<<<<<<<.>>>>>>.>>>...>>>>
>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<
.<<<....>>>.>>>.....>>>...<<<..<<.<<........>>>>.>
>>....>>>>>>>>>...<<.......>>......>>>>>>...>..>.>
>...<<<<<....<.<<<....>>>.><<<<<<<<<.....<<...<<<<
<<<...<<<....<<<....<<<..>>>....>>>..>.>>...>>>>>>
>.....<<<.<<<<<.<<.....>>>>>>>>>>...........>>...>
>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>...<<<<......>
>>>..<<<<<<<...<<<(((......<..<<<<........<.......
....<<<.<<<<<<<<<<..>>>>>>>>>>>>>..........))).>..
..>>>>.>.........>>>...>>>>>>>((((.<<<<<..........
.>>>>.........>>>>>))))....>>>>>....<<<<<<<<......
...<<<..<<<....>>>.>>>.......>>>>>>>>........>>>>>
>..............<<<<<<<..................>>>>>>>...
.................<<<<<....<<.....>>..>>>>>....<<..
........<<.<<<<<......>>>>...............<<...>>..
....>.>>..........<<<...........>....>>.>>........
... |
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| PDB | 5t2a Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. |
| Resolution | 2.9 Å |
Binding residue
(original residue number in PDB) | G2 F4 K12 K14 S15 H34 R40 R41 R44 R49 M50 K54 T55 R67 R68 G69 G70 R71 H76 Y81 G82 K83 P84 K85 M92 K93 L94 N95 K96 N97 N98 R105 G111 N112 W120 M138 K140 T141 R144 R147 W150 S154 H156 K157 Q161 R162 L164 S166 R169 K170 H171 R172 R175 H176 K177 G178 H179 K180 S182 K183 R185 S187 Y188 A190 W192 R193 R194 N195 F200 R202 R204 |
Binding residue
(residue number reindexed from 1) | G1 F3 K11 K13 S14 H33 R39 R40 R43 R48 M49 K53 T54 R66 R67 G68 G69 R70 H75 Y80 G81 K82 P83 K84 M91 K92 L93 N94 K95 N96 N97 R104 G110 N111 W119 M137 K139 T140 R143 R146 W149 S153 H155 K156 Q160 R161 L163 S165 R168 K169 H170 R171 R174 H175 K176 G177 H178 K179 S181 K182 R184 S186 Y187 A189 W191 R192 R193 N194 F199 R201 R203 |
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