Structure of PDB 5opt Chain O Binding Site BS01

Receptor Information
>5opt Chain O (length=190) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSAKAPKLFNKWSYENLQTTEIALSDHISKTATYVPHSAGRWQKKRFRKA
RIPIVERLTNGLMFKGRGNGKKLQAVRLVKHTLEIIHLLTDQNPLQVVID
AVSKGAPREDSTRVGSGGVVRRQAVDVSPMRRVNEAIYLMCKGAREAAFR
NLKTLPECLADEIVNASKGSSNSYAIKKKDEVERVAKANR
Ligand information
>5opt Chain E (length=2022) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcauugcaggaaucugcgcauggcucauua
caucagacguaaucugccgcaaaaaucuugcggucuccgcaacauuggau
aacuuggcgaaacgccaagcuaauacaugaaccaaccggauguucucugu
uccggcggcagggcaaccugcugccaugggacguccagcgaaugaaugaa
aguaaaaccaaugccuucaccggcaguaacacucagaaguguugauucaa
uucauuccgugcgaaagccggguuuuuuuauccggcgucuuuugacgaac
aacugcccuaucagccagcgauggccguguaguggacugccauggcguug
acgggagcgggggauuaggguucgauuccggagagggagccugagaaaua
gcuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugucaaa
aaaaaaagaugaggcagcgaaaagaaauagagccgacagugcuuuugcau
ugucguuuucaaugggggauauuuaaacccauccaaaaucgaguaacaau
uggaggacaagucuggugccagcacccgcgguaauuccagcuccaaaagc
guauauuaaugcuguugcuguuaaaggguucguaguugaauugagggccu
cuaaggcgcaaugguuuagucccauccacuucggauuggugacccaugcc
cuugugguccgugaacgacauucagaaacaaaaaacacgggagugguacc
uuuccugauuaucgcaugucaugcaugccagagggcgcccgugauuuuuu
acugugacuaaaaaagugugaccaaagcagucauucgacuugaauuagaa
agcaugggauaacaaaggagcagccucugggccaccguuucggcuuuugu
ugguuuuaaaaguccauuggagauuauggggcagugugacaagcggcugu
cgccuuugugggaaaugccuucccucaacucacggcauccaggaaugaag
gaggguaguucgggggagaacguacuggugcgucagaggugaaauucuua
gaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuucc
ucaaucaagaaccaaaguguggggaucgaagaugauuagagaccauugua
guccacacugcaaacgaugacacccaugaauuggggacucagcacguuau
cugacuucuucacgcgaaagcuuugagguuacagucucaggggggaguac
guucgcaagagugaaacuuaaagaaauugacggaauggcaccacaagacg
uggagcgugcgguuuaauuugacucaacacggggaacuuuaccagauccg
gacagggugaggauugacagauugaguguucuuucucgauccccugaaug
guggugcauggccgcuuuuggucgguggagugauuuguuugguugauucc
gucaacggacgagauccaagcugcccaguaggauucagaauugcccaucc
cuuccgcggguuuuacccaagggggggcgguauucgcuuguauccuucuc
ugcgggauuccuuguuuugcgcaaggugagauuuugggcaacagcagguc
ugugaugcuccucaauguucugggcgacacgcgcacuacaaugucaguga
gaacaagaaaaacgacucuugucggaccuacuugaucaaaagagugggaa
aaccccggaaucacguagacccacuugggaccgaguauugcaauuauugg
ucgcgcaacgaggaaugucucguaggcgcagcucaucaaacugugccgau
uacgucccugccauuuguacacaccgcccgucguuguuuccgaugauggu
gcaauacaggugaucggacagucgagugcuucacuugaccgaaaguucac
cgauauuucuucaauagaggaagcaaaagucguaacaagguagcuguagg
ugaaccugcagcuggaucauuu
...<<<<....{{{{.>>>>{{{{.[[[[[[...[[[..........[[[
.[[[..<<....<<....<<<<...>>>>...>>.>>......{{.....
...[[[..[[..[[...[[.[[.....<<<<<<...>>>>>>...<<...
..<<<<<<.....>>>>>>......>>..........<<<<<.<<<....
...<<<<<<<<<....>>>>>>>>>...>>>>>>>>.[[((((((((...
...<<<<<<<<<<<<......>>>.........................)
)))))))...]]....<<<<<<........>>>>>>...]].]]..]]]]
..]]].<<<....<<<....<<<<<.<<.......>>.>>>>>>>>....
..>>>..<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<<<<....>>>>...]]]]]].........<<<....<<<...
.......>>>..>>>.......]]]....<<<.<<<<<<<<<....>>>>
>>>>>..>>>.....<<<<............>>>.....>.........<
<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>..]]
]]]]}}}}.........{{{{{.....[[[[...[[[..{....<<<<<.
<.<<<<.<<<.<<<.............................>>>>>>>
>>>>.>>>>>.........................<<<<<<.......<<
<<<............<<.......>>....>>>>>..>>>>>>.....<<
<<<<<<.......<<...<.......>..<<<....>>>.....>>....
..>>>>>..>>>...........[[..(((((..<<.....>>.....>>
>>>>>>>....)))))..]].......<<<.<.<<<.<.....<<<...>
>>........<<<......>>>......>.>>>.>..>>>.....}....
..<<<<<..<<...<<<<<<<<..<<<<<<<<...<<<......>>>...
...>>>>>>>.>.>>.......<<....>>.>>>>>>..>>.>>>.>>..
..]]]...]]]]...<<<<<<<<...<...<<<<.........>>>>...
>>>>>>>>>.........<<<.<<...<..<<<<<..............>
>>>>..>......<<..}}>>.....>>.....>>>.}}}.<<<......
<<<<....>>>>....>>>..}}}}..<<<<<.<<<<<<<..<<.<<<<<
<.....<<<<<........<<........>>..........<<.<<....
..<<<<<........<<.<<<........>>>.>>......>>>>>...<
<.<<<.....<<<<<<....<<<.<<<<<....>>>...<<<......>>
>...>>.>>>....<<<<<.<<<<.....<<<<<....<.........<.
<<<<<..<<<.....>>>..>>>>>.>......>.......>>>>>....
.>>>>...<..<.<<.....>>>..>.......>>>>>....>>>.>>>.
......>>>>>.......>.>.>>.......>>>>>..............
..........................<<<<<<<........>>>>>>>..
..........................<....<<<................
>>>.....>.....>>>>>>....<<<<<<<.........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<<<<<..<<.<<<.
<.<<<<..<<<<<.<...<.<<<<<<<<...>>>>>>>>.>...>.>>>>
>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>.....<<<<<<<<<
....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5opt The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		G40 R41 W42 Q43 K45 R46 K49 N60 M63 F64 K65 R67 G68 N69 G70 K72 Q74 R77 R131 N134 Y138 A148 F149 R150 N151 L152 K153 L155
Binding residue
(residue number reindexed from 1)		G40 R41 W42 Q43 K45 R46 K49 N60 M63 F64 K65 R67 G68 N69 G70 K72 Q74 R77 R131 N134 Y138 A148 F149 R150 N151 L152 K153 L155
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5opt, PDBe:5opt, PDBj:5opt
PDBsum5opt
PubMed29107485
UniProtQ4E0Q3

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