Structure of PDB 5crj Chain O Binding Site BS01

Receptor Information
>5crj Chain O (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIA
SIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNN
NLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAG
LSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLV
LICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIA
LAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCN
LSTLNITLLSWSKKRYEAKLKKLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5crj Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion.
Resolution2.59 Å
Binding residue
(original residue number in PDB)
R92 R127 R162 S163 E165 T198 N199 R202 P242 F243 R350 T379 W383 K391 K394
Binding residue
(residue number reindexed from 1)
R20 R55 R90 S91 E93 T126 N127 R130 P170 F171 R278 T307 W311 K319 K322
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003690 double-stranded DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5crj, PDBe:5crj, PDBj:5crj
PDBsum5crj
PubMed26523681
UniProtQ99551|MTEF1_HUMAN Transcription termination factor 1, mitochondrial (Gene Name=MTERF1)

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